3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one Chemical Properties

Melting point:

126-130 °C(lit.)

Boiling point:

281.4±36.0 °C(Predicted)

Density 

1.07

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

pka

6.25±0.70(Predicted)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

2933399990

3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one Usage And Synthesis

Synthesis

3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one was synthesised based on the literature. The reaction of (2g, 16.5mmol) of 2-acetylpyridine and DMF dimethyl acetal(7.84g) were suspended in 11ml of xylene and stir this reaction mixture for 16h at 110℃. Into the resulting mixture 10 ml of hexane added yellow colour precipitate was formed and allows stirring for 20min at 3℃. Resulting mixture was filtered and dried in vacuum to get a yellow colour powder.

Uses

3-(Dimethylamino)-1-(2-pyridyl)-2-propen-1-one may be used in the preparation of the 5-(heteroaryl)isoxazole derivatives, 5-(2-pyridyl)isoxazole and 3-methyl-5-(2-pyridyl)isoxazole. It may also be used to synthesize 7-(2-pyridyl)-1,2,4-triazolo[1,5-a]pyrimidine.

General Description

3-(Dimethylamino)-1-(2-pyridyl)-2-propen-1-one (1-(2′-Pyridyl)-3-dimethylamino-2-propen-1-one), an enaminone, is a hemilabile hybrid ligand. The preparation of cationic mononuclear rhodium(I) or iridium(I) complexes containing 3-(dimethylamino)-1-(2-pyridyl)-2-propen-1-one have been reported.

3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one(66521-54-8)Related Product Information

• 3-DIMETHYLAMINO-1-PYRIDIN-4-YL-PROPENONE
• (E)-1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-3-(DIMETHYLAMINO)-2-PROPEN-1-ONE
• 3-(1,3-DIHYDRO-ISOINDOL-2-YL)-1-PYRIDIN-2-YL-PROPENONE
• 1H-Indolo(3,2-c)quinoline-1,4(11H)-dione, 2-(1-aziridinyl)-6-methyl-
• 3-(DIMETHYLAMINO)-1-(2-PYRIDINYL)-2-BUTEN-1-ONE
• 1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-3-(DIMETHYLAMINO)-2-BUTEN-1-ONE
• 3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one
• 1-(6-BROMO-2-PYRIDINYL)-3-(DIMETHYLAMINO)-2-PROPEN-1-ONE