FLONICAMID Chemical Properties

Melting point:

157.5°

Boiling point:

406.6±45.0 °C(Predicted)

Density 

1.377±0.06 g/cm3(Predicted)

storage temp. 

-20°C Freezer

solubility 

DMSO (Slightly), Methanol (Slightly), Ethanol (Slightly, Heated)

pka

10.99±0.46(Predicted)

form 

Solid

color 

Light Beige to Beige

InChI

InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)

InChIKey

RLQJEEJISHYWON-UHFFFAOYSA-N

SMILES

C1=NC=CC(C(F)(F)F)=C1C(NCC#N)=O

LogP

0.840 (est)

EPA Substance Registry System

Flonicamid (158062-67-0)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22

WGK Germany 

2

HS Code 

29333990

Hazardous Substances Data

158062-67-0(Hazardous Substances Data)

Toxicity

LD50 in male, female rats (mg/kg): 884, 1768 orally; in rats (mg/kg): >5000 dermally; in rats (mg/m3): >4900 by inhalation; LC50 in carp, rainbow trout (mg/l): >100, >91.9 (Morita)

FLONICAMID Usage And Synthesis

Description

Flonicamid is a pyridinecarboxamide insecticide. It inhibits the brown planthopper (N. lugens) inward-rectifying potassium channel K_ir1 (IC₅₀ = 0.64 μM). Flonicamid (100 μg/ml) inhibits aphid (M. persicae) salivation and sap ingestion during feeding on Japanese radish leaves. It induces toxicity in the aphid species A. gossypii, R. padi, S. graminum, and L. erysimi (LC₅₀s = 0.64, 0.74, 0.78, and 2.01 μg/ml, respectively) and rats (LD₅₀ = ≥844 mg/kg). Formulations containing flonicamid have been used for the control of pest insects in agriculture.

Uses

Flonicamid is a novel insecticide with rapid inhibitory effect against aphid feeding. Useful in cannabis testing kits as a component of pesticide mixes (P698240).

Uses

Flonicamid is an novel insecticide with rapid inhibitory effect against aphid feeding.

Uses

Insecticide.

Definition

Flonicamid is a chordotonal modulator and novel systemic insecticide that has been used frequently for controlling a broad range of insect pests. The risk of flonicamid resistance was assessed through laboratory selection and determining inheritance pattern and cross-resistance potential to five insecticides in house fly, Musca domestica L. Very low to high flonicamid resistance in M. domestica populations was found compared with the susceptible strain (SS).

Definition

ChEBI: A pyridinecarboxamide that is nicotinamide substituted by a trifluoromethyl group at position 4 and a cyanomethyl group at the carbamoyl nitrogen atom.

Application

With foliar spray application at the rates of 50-100 g a.i./ha, onicamid exhibits excellent aphicidal activity and also shows good insecticidal activity against other sucking insect pests such as thrips, whiteies, planthoppers, leafhoppers, plant bugs, and mealybugs in fruit trees, cereals, rice, potatoes, cotton, vegetables and ornamentals. Flonicamid soil applications also provide control of the foliar pests mentioned above.

Mode of action

Flonicamid rapidly inhibits the feeding behavior of aphids, and has better action through ingestion than by contact. Its mode of action is different from other insecticides such as neonicotinoids, pymetrozine and pyriuquinazon. Flonicamid belongs to IRAC Group 29 and is the only insecticide in this class.

FLONICAMID(158062-67-0)Related Product Information

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• FLONICAMID