Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Chemical Reagents >  Organic reagents >  Aromatic acids >  5-Fluorosalicylic acid

5-Fluorosalicylic acid

Basic information Safety Supplier Related

5-Fluorosalicylic acid Basic information

Product Name:
5-Fluorosalicylic acid
Synonyms:
  • BUTTPARK 34\01-09
  • 5-FLUORO-2-HYDROBENZOIC ACID
  • 5-fluoro-2-hydroxybenzoic
  • 5-FLUORO-2-HYDROXYBENZOIC ACID
  • 5-FLUOROSALICYLIC ACID
  • 2-HYDROXY-5-FLUOROBENZOIC ACID
  • RARECHEM AL BE 0856
  • 5-Fluoro-2-Hydroxy Benzoic Acid 5-Fluoro Sallicylic Acid 2-Hydroxy-5-Fluoro Benzoic Acid
CAS:
345-16-4
MF:
C7H5FO3
MW:
156.11
EINECS:
206-455-3
Product Categories:
  • Fluorine series
  • Aryl Fluorinated Building Blocks
  • Building Blocks
  • C7
  • Carbonyl Compounds
  • Carboxylic Acids
  • Chemical Synthesis
  • Fluorinated Building Blocks
  • Organic Building Blocks
  • Organic Fluorinated Building Blocks
  • Other Fluorinated Organic Building Blocks
  • Acids & Esters
  • Fluorine Compounds
  • Phenols
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
Mol File:
345-16-4.mol
More
Less

5-Fluorosalicylic acid Chemical Properties

Melting point:
177-179 °C (lit.)
Boiling point:
307.4±27.0 °C(Predicted)
Density 
1.3290 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
form 
powder to crystal
pka
2.68±0.10(Predicted)
color 
light brown
Water Solubility 
Slightly soluble in water.
BRN 
2209120
InChI
InChI=1S/C7H5FO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,(H,10,11)
InChIKey
JWPRICQKUNODPZ-UHFFFAOYSA-N
SMILES
C(O)(=O)C1=CC(F)=CC=C1O
CAS DataBase Reference
345-16-4(CAS DataBase Reference)
NIST Chemistry Reference
Benzoic acid, 5-fluoro-2-hydroxy-(345-16-4)
More
Less

Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38-37/38-36
Safety Statements 
26-36-37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29182900
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

MSDS

More
Less

5-Fluorosalicylic acid Usage And Synthesis

Description

5-Fluorosalicylic acid (FSA) is prepared by reacting p-fluorophenol with carbon dioxide under heated and pressurised conditions in the presence of an alkaline catalyst. It is an excellent chelating agent which forms highly fluorescent ternary complexes with terbium ions (Tb³⁺), and is utilised in immunological assays. FSA also serves as a building block for active pharmaceutical ingredients (APIs), such as fluorinated deferoxamine used in the treatment of chronic iron overload.

Chemical Properties

light yellow powder

Uses

5-Fluorosalicylic acid was used as internal standard in the quantification of salicylic acid.

Synthesis Reference(s)

Tetrahedron, 52, p. 23, 1996 DOI: 10.1016/0040-4020(95)00867-8

5-Fluorosalicylic acidSupplier

BEIJING GOLDEN OLIVE COMPANY Gold
Tel
15311296095
Email
mary@goldolive.com
Fuxin Pharmaceutical Gold
Tel
021-50872116 13611907556
Email
contact@fuxinpharm.com
Hangzhou Chemtrue Bio-Tech Co.,Ltd. Gold
Tel
0571-86828652 18857119830
Email
sales@chemtrue-bio.com
Wuhan Fortuna Chemical Co., Ltd Gold
Tel
027-59207852 13308628970
Email
buy@fortunachem.com
https://www.shachemlin.cn/ Gold
Tel
021-68080707 18079794756
Email
soloman.lee@chemlin.com.cn