4-Methylaniline hydrochloride
4-Methylaniline hydrochloride Basic information
- Product Name:
- 4-Methylaniline hydrochloride
- Synonyms:
-
- p-Toluidine hydrochlori
- 4-methylaniliniumchloride
- 4-methylbenzenaminehydrochloride
- 4-methyl-benzenaminhydrochloride
- p-Toluidine hydrochloride purum, >=99.0% (AT)
- p-Toluidinium chloride for synthesis
- 4-TOLUIDINE HYDROCHLORIDE
- 4-AMINO-1-METHYLBENZENE HYDROCHLORIDE
- CAS:
- 540-23-8
- MF:
- C7H10ClN
- MW:
- 143.61
- EINECS:
- 208-740-8
- Product Categories:
-
- Nitrogen Compounds
- Organic Building Blocks
- Amine Salts
- Building Blocks
- Chemical Synthesis
- Mol File:
- 540-23-8.mol
4-Methylaniline hydrochloride Chemical Properties
- Melting point:
- 243-245 °C(lit.)
- Density
- 1.193 g/cm3
- storage temp.
- Store below +30°C.
- Water Solubility
- Soluble in water
- solubility
- DMSO (Sparingly), Methanol (Slightly)
- form
- powder to crystal
- color
- White to Gray to Red
- BRN
- 3557540
- Stability:
- Hygroscopic
- CAS DataBase Reference
- 540-23-8(CAS DataBase Reference)
- EPA Substance Registry System
- p-Toluidine hydrochloride (540-23-8)
Safety Information
- Hazard Codes
- T,N
- Risk Statements
- 23/24/25-36-40-43-50
- Safety Statements
- 28-36/37-45-61
- RIDADR
- UN 2811 6.1/PG 1
- WGK Germany
- 3
- RTECS
- XU7525000
- HazardClass
- 6.1(a)
- PackingGroup
- II
- HS Code
- 29214300
MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
4-Methylaniline hydrochloride Usage And Synthesis
Chemical Properties
white to light beige crystalline powder, crystals
Uses
p-Toluidine Hydrochloride acts as a reagent for the preparation and biological activity of N-acylleucine (arylaminoethyl)amides as non-covalent inhibitors of cathepsin K, L and S. Catalyst in the chemistry of azasteroids.
General Description
Off-white to grayish-white crystals.
Air & Water Reactions
Water soluble. May be sensitive to moisture.
Reactivity Profile
4-Methylaniline hydrochloride reacts with oxidizing and alkali materials. .
Fire Hazard
Flash point data for 4-Methylaniline hydrochloride are not available, but 4-Methylaniline hydrochloride is probably combustible.
Safety Profile
Poison by intraperitoneal route. Moderately toxic by ingestion. Questionable carcinogen with experimental carcinogenic and tumorigenic data. When heated to decomposition it emits very toxic fumes of NOx and HCl. See also p-TOLUIDINE.
Purification Methods
Crystallise the salt from MeOH containing a few drops of conc HCl or aqueous EtOH. Dry it under vacuum over paraffin chips. [Beilstein 12 II 587, 12 III 2021, 12 IV 1869.]
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