2-Chlorobenzothiazole Chemical Properties

Melting point:

21-23 °C (lit.)

Boiling point:

141 °C/30 mmHg (lit.)

Density 

1.303 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.637(lit.)

Flash point:

>230 °F

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

pka

-0.23±0.10(Predicted)

form 

Liquid

Specific Gravity

1.3711.303

color 

Clear yellow to yellow-brownish

Water Solubility 

insoluble

BRN 

116316

CAS DataBase Reference

615-20-3(CAS DataBase Reference)

NIST Chemistry Reference

Benzothiazole, 2-chloro-(615-20-3)

EPA Substance Registry System

2-Chlorobenzothiazole (615-20-3)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

36/37/38-22-20/21/22

Safety Statements 

23-24/25-37/39-26-36

RIDADR 

2810

WGK Germany 

3

RTECS 

DL3150000

Hazard Note 

Irritant

TSCA 

Yes

HS Code 

29342080

MSDS

• Language:English Provider:2-Chloro-1,3-benzothiazole
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2-Chlorobenzothiazole Usage And Synthesis

Chemical Properties

CLEAR YELLOW TO YELLOW-BROWNISH LIQUID

Uses

2-Chloro-1,3-benzothiazole is used in the synthesis of CBTs which are good building blocks for bioluminescent compounds for imaging.

Uses

2-Chlorobenzothiazole was used in the synthesis of:

• (RS)- and (S)-lubeluzole
• (1,3-benzothiazol-2-yl) amino-9-(10H)-acridinone derivatives
• 4H-thieno[2′,3′:4,5]pyrimido[2,1-b]benzothiazole derivatives

Purification Methods

It is purified by fractional distillation in vacuo. The 2-chloro-3-methylbenzothiazolinium 2,4-dinitrobenzenesulfonate crystallises from Ac2O, m 162-163o(dec). [Young & Amstutz J Am Chem Soc 73 4773 1951, Brower et al. J Org Chem 19 1830 1954, Hunter & Jones J Chem Soc 2190 1930, Beilstein 27 H 44, 27 II 18, 27 III/IV 1072.]

2-Chlorobenzothiazole(615-20-3)Related Product Information

• Benzothiazole
• 2-Mercaptobenzothiazole
• 2,2'-Dithiobis(benzothiazole)
• Difluorochloromethane
• 2-Chloro-4-methylbenzothiazole
• 2-Chloro-4-fluorobenzothiazole
• 2-Chloro-6-methylbenzothiazole
• Benzothiazole, 2,5-dichloro- (7CI,8CI,9CI)
• 6-isopropyl-2-chlorobenzothiazole
• 4-BROMO-2-CHLOROBENZOTHIAZOLE
• 2-Chloro-6-fluorobenzothiazole
• 2,6-Dichlorobenzothiazole
• 6-Methoxy-2-chlorobenzothiazole
• 2-Chloro-6-nitrobenzothiazole
• 2,4-Dichlorobenzothiazole
• 2-(4-ethylphenyl)thiazole
• 2-AMINO-6-CHLOROBENZOTHIAZOLE
• 2-BROMO-4-CHLOROBENZOTHIAZOLE