Solitomab Chemical Properties

form 

Liquid

color 

Colorless to light yellow

Solitomab Usage And Synthesis

Uses

Solitomab (AMG 110) is a bispecific anti-CD3 and anti-epithelial-cell-adhesion-molecule (EpCAM) antibody. Solitomab can be used for the research of primary uterine and ovarian carcinosarcoma cancer[1][2].

References

[1] Ferrari F, et al. Solitomab, an EpCAM/CD3 bispecific antibody construct (BiTE?), is highly active against primary uterine and ovarian carcinosarcoma cell lines in vitro. J Exp Clin Cancer Res. 2015 Oct 17;34:123. DOI:10.1186/s13046-015-0241-7
[2] English DP, et al. Solitomab, an epithelial cell adhesion molecule/CD3 bispecific antibody (BiTE), is highly active against primary chemotherapy-resistant ovarian cancer cell lines in vitro and fresh tumor cells ex vivo. Cancer. 2015 Feb 1;121(3):403-12. DOI:10.1002/cncr.29062

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