ChemicalBook > Product Catalog > Biochemical Engineering > Inhibitors > Neuronal Signaling > Opioid Receptor Antagonists > JTC 801
JTC 801
JTC 801 Basic information
- Product Name:
- JTC 801
- Synonyms:
-
- JTC 801
- N-(4-Amino-2-methyl-6-quinolinyl)-2-[(4-ethylphenoxy)methyl]benzamidehydrochloride
- N-(4-Amino-2-methyl-6-quinolinyl)-2-[(4-ethylphenoxy)methyl]benzamide monohydrochloride
- JTC 801 HCl
- JTC-801 hydrochloride
- JTC-801/JTC801
- N-(4-AMino-2-Methyl-quinolin-6-yl)-2-(4-ethyl-phenoxyMethyl)-benzaMide hydrochloride
- Benzamide,N-(4-amino-2-methyl-6-quinolinyl)-2-[(4-ethylphenoxy)methyl]-, hydrochloride
- CAS:
- 244218-51-7
- MF:
- C26H25N3O2.ClH
- MW:
- 447.963
- Product Categories:
-
- Inhibitors
- Mol File:
- 244218-51-7.mol
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JTC 801 Chemical Properties
- Melting point:
- 235℃
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- DMSO: ≥20mg/mL
- form
- powder
- color
- tan
- InChIKey
- NQLIYKXNAXKMBL-UHFFFAOYSA-N
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JTC 801 Usage And Synthesis
Uses
JTC 801 is a novel opioid receptor-like1 (ORL1) receptor antagonist.
Biological Activity
High affinity, selective NOP receptor antagonist (K i = 8.2 nM). Displays approximately 12.5-, 129- and 1055-fold selectivity over human μ -, κ - and δ -opioid receptors respectively. In vivo shows anti-nociceptive effects in acute pain models. Orally active.
storage
Desiccate at RT
JTC 801Supplier
Shanghai Boyle Chemical Co., Ltd.
- Tel
- sales@boylechem.com
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Chembest Research Laboratories Limited
- Tel
- 021-20908456
- sales@BioChemBest.com
JinYan Chemicals(ShangHai) Co.,Ltd.
- Tel
- 13817811078
- sales@jingyan-chemical.com
Shanghai Sphchem Co., Ltd.
- Tel
- 21-21-56491756 13512199871
- sales@panhongchem.com