PALMITOYL CARNITINE
PALMITOYL CARNITINE Basic information
- Product Name:
- PALMITOYL CARNITINE
- Synonyms:
-
- (-)-[(R)-3-Carboxylato-2-(palmitoyloxy)propyl]trimethylaminium
- (2R)-3-Carboxylato-N,N,N-trimethyl-2-[(1-oxohexadecyl)oxy]-1-propanaminium
- Hexadecanoylcarnitine
- Palmitoyl L-carnitine
- Palmitylcarnitine
- C02990
- 1-PropanaMiniuM, 3-carboxy-N,N,N-triMethyl-2-[(1-oxohexadecyl)oxy]-, inner salt, (2R)-
- O-palmitoyl-L-carnitine
- CAS:
- 2364-67-2
- MF:
- C23H45NO4
- MW:
- 0
- Mol File:
- 2364-67-2.mol
PALMITOYL CARNITINE Chemical Properties
- storage temp.
- 2-8°C
- solubility
- Soluble in DMSO
- optical activity
- [α]/D -17±2°, c = 1 in methanol
- BRN
- 4152034
PALMITOYL CARNITINE Usage And Synthesis
Uses
L-?Palmitoyl Carnitine is used as a diagnostic agent in the investigation of drug toxicity with respect to the liver. Acts as a biomarker in the study of metabolism in metabolic diseases.
Definition
ChEBI: An O-acyl-L-carnitine in which the acyl group is specified as palmitoyl (hexadecanoyl).
General Description
Palmitoyl-L-carnitine (PLC) belongs to the class of long chain acylcarnitine compounds. It is an acyl-chain ester, which can be obtained from L-carnitine via acylcarnitine family transferase. PLC is reported to be used for the phospholipid reacylation in erythrocyte membrane ghosts.
Biochem/physiol Actions
L-Palmitoylcarnitine can change the activity of several enzymes and transporters, localized in the membrane and facilitates the transfer of long-chain fatty acids from cytoplasm into mitochondria during the oxidation of fatty acids. L-Palmitoylcarnitine accumulates in ischemic myocardium and potentially contribute to myocardial damage through alterations in membrane molecular dynamics.
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