Product Identification

Product Name

3-Thiosemicarbazide

Synonyms

Hydrazinecarbothioamide
N-Aminothiourea
N-Ethylpiperazine

CAS

5308-25-8

CAS

79-19-6

Formula

C6H14N2

Formula

CH5N3S

Molecular Weight

91.14

Molecular Weight

114.19

EINECS

201-184-7

EINECS

226-166-6

RTECS

TM0815500

RTECS

VT4200000

RTECS Class

Agricultural Chemical and Pesticide; Tumorigen; Mutagen

RTECS Class

Other

Merck

12,9499

Beilstein/Gmelin

506320

Beilstein/Gmelin

102971

Beilstein Reference

5-23-01-00132

Beilstein Reference

4-03-00-00374

EC Class

flammable

EC Class

very toxic

Physical and Chemical Properties

Appearance

A white crystalline powder and is odorless.

Appearance

Clear, colorless liquid.

Solubility in water

Soluble

Melting Point

178 - 180

Melting Point

-60

Boiling Point

157

Vapor Pressure

105.008 (92.25 C)

Density

0.8989 g/cm3 (20 C)

Partition Coefficient

-.73

Usage

Reagent for ketones and certain metals, photography, rodenticide.

Vapor Density

3.94

Refractive Index

1.463 (20 C)

First Aid Measures

Ingestion

Causes gastrointestinal tract burns. May cause perforation of the digestive tract. Ingestion of large amounts may cause CNS depression. May cause systemic effects.

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. SPEED IS ESSENTIAL. A DOCTOR MUST BE NOTIFIED AT ONCE.

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. Do not use mouth-to-mouth respiration if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Inhalation

Causes chemical burns to the respiratory tract. Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. May cause systemic effects. May cause burning sensation in the chest.

Skin

Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Skin

Causes skin burns. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Eyes

Causes eye burns. May cause chemical conjunctivitis and corneal damage.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. Flammables-area. Store in a cool, dry area away from incompatible substances.

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked. Keep containers tightly closed.

Handling

Use only in a well ventilated area. Use spark-proof tools and explosion proof equipment. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not get on skin or in eyes. Do not ingest or inhale. Discard contaminated shoes.

Handling

Wash thoroughly after handling. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Do not breathe dust, vapor, mist, or gas. Keep container tightly closed. Avoid ingestion and inhalation. Use only in a chemical fume hood.

Hazards Identification

Inhalation

Causes respiratory tract irritation.

Skin

Causes skin irritation.

Eyes

May cause eye irritation.

Ingestion

May be fatal if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea.

Hazards

Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.

Hazards

When heated to decomposition, very toxic fumes of sulfur oxides and nitrogen oxides are emitted.

EC Risk Phrase

R 10 34

EC Risk Phrase

R 28 52/53 63

EC Safety Phrase

S 22 28 36/37/39 45 61

EC Safety Phrase

S 26 36/37/39 45

UN (DOT)

2734

UN (DOT)

2811

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

CNS excitation and seizures may occur. Thiosemicarbazide was teratogenic in test animals.

Exposure Effects

Effects may be delayed.

Poison Class

2

Fire Fighting Measures

Flash Point

49

Autoignition

> 350

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Runoff from fire control or dilution water may cause pollution. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective.

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Fire Potential

Flammable/combustible material. May be ignited by heat, sparks or flames.

Fire Potential

Nonflammable.

Accidental Release Measures

Small spills/leaks

Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Disposal Code

9

Stability

No data.

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents - strong acids - strong bases.

Incompatibilities

Strong oxidizing agents.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide.

Decomposition

Nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Combustion Products

Fire will produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2734

UN Number

2811

Hazard Class

6.1

Hazard Class

8

Packing Group

I; II

Packing Group

I; II; III

HS Code

2930 90 70

HS Code

2933 59 95