Product Identification

Product Name

2-Oxetanone

Synonyms

1,3-Propiolactone
2-Oxetanone
3-Hydroxy-b-lactone
Hydroacrylic acid
Propanolide
Propiolactone

CAS

57-57-8

Formula

C3H4O2

Molecular Weight

72.06

EINECS

200-340-1

RTECS

RQ7350000

RTECS Class

Agricultural Chemical and Pesticide; Tumorigen; Mutagen

Merck

12,8005

Beilstein/Gmelin

1360

Beilstein Reference

5-17-09-00003

EC Index Number

606-031-00-1

EC Class

Carcinogenic Category 2; Very toxic; Irritant

Physical and Chemical Properties

Appearance

A colorless liquid with a slightly sweetish, pungent odor.

Solubility in water

370 g/L (25 C)

Melting Point

-31.2

Boiling Point

155

Vapor Pressure

2.2 (25 C)

Density

1.145 g/cm3 (20 C)

Partition Coefficient

.462

Heat Of Vaporization

39.9 kJ/mol

Heat Of Combustion

-1410 kJ/mol

Usage

Versatile intermediate in organic synthesis, disinfectant.

Vapor Density

2.5

Refractive Index

1.4138 (20 C)

First Aid Measures

Ingestion

Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Skin

Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Keep away from sources of ignition. Store in a tightly closed container. Deep freeze (below -20 C). Store protected from light. Store under argon.

Handling

Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.

Hazards Identification

Inhalation

Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema. Toxic if inhaled. May cause burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting. Inhalation may cause sore throat, shortness of breath, labored breathing, coughing, and pulmonary edema.

Skin

May be harmful if absorbed through the skin. Causes irritation with burning pain, scaling, itching and redness. May cause erythema and blistering.

Eyes

May cause conjunctivitis. Causes redness and pain. Causes eye irritation and burns. May cause permanent corneal opacification.

Ingestion

May be harmful if swallowed. May cause irritation of the digestive tract and possible burns. May cause nausea, vomiting, headache, cramps, chills and drowsiness.

Hazards

Containers may explode. When heated to decomposition, it emits acrid smoke and fumes. Stable when stored at 41F. Avoid storing in areas of exposure to the direct rays of the sun and in areas of high fire hazard. Tends to polymerize on storage. Avoid elevated temperatures.

UN (DOT)

2810

Exposure Controls/Personal Protection

Personal Protection

Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

May cause cancer in humans. Animal studies have reported the development of tumors.

Exposure limit(s)

TLV: 0.5 ppm; 1.5 mg/m3 A3 (ACGIH 1997). OSHA PEL: 1910.1013 See Appendix B NIOSH REL: Ca See Appendix A NIOSH IDLH: Potential occupational carcinogen N.D

Poison Class

1*

Fire Fighting Measures

Flash Point

74

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire. Combustible Liquid. Extinguishing media: Use water spray to cool fire-exposed containers. In case of fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Upper exp. limit

25.1

Lower exp. limit

2.9

Fire Potential

Moderately flammable. Combustion with moderate heating.

Accidental Release Measures

Small spills/leaks

Avoid runoff into storm sewers and ditches which lead to waterways. Neutralize spill with sodium bicarbonate. Cover with sand, dry lime or soda ash and place in a closed container for disposal. Remove all sources of ignition. Provide ventilation.

Stability and Reactivity

Stability

Stable when stored at +5 C in glass containers.

Incompatibilities

Strong oxidizing agents, strong bases, strong acids, acetates, halogens, thiocyanates, 2-aminoethanol, ammonium hydroxide, aniline, chlorosulfonic acid, ethylene diamine, ethyleneimine, hydrochloric acid, hydrofluoric acid, nitric acid, oleum, pyridine, sodium hydroxide, sulfuric acid.

Decomposition

Carbon monoxide, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2810

Hazard Class

6.1

Packing Group

I; II; III