Product Identification

Product Name

3,6-Dihydroxy-2,4,5,7-tetrabromospiro(xanthene-9,3'-phthalide)

Synonyms

2',4',5',7'-Tetrabromo-3',6'-dihydroxyspiro[Isobenzofuran-1(3H),9'-[9H]xanthen]-3-one
2',4',5',7'-Tetrabromofluorescein
3,6-Dihydroxy-2,4,5,7-tetrabromospiro[xanthene-9,3'-phthalide]
C.I. 45380:2
Eosine acid
Solvent Red 43

CAS

15086-94-9

Formula

C20H8Br4O5

Molecular Weight

647.91999999999996

EINECS

239-138-3

RTECS

LM5800000

RTECS Class

Tumorigen; Mutagen

Beilstein/Gmelin

63410

Beilstein Reference

5-18-09-00541

Physical and Chemical Properties

Appearance

Pink to orange powder

Solubility in water

Insoluble

Melting Point

295

pKa/pKb

4.84 (pKa)

Usage

Biological stain.

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Use with adequate ventilation.

Hazards Identification

Inhalation

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Effects may be delayed.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion. To extinguish fire, use water fog, dry chemical, carbon dioxide, or regular foam. Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen bromide.