Product Identification

Product Name

C.I. 45350

Synonyms

9-(o-Carboxyphenyl)-6-hydroxy-3H-xanthen-3-one, disodium salt
D and C Yellow No. 8
Fluorescein sodium
Fluorin
Resorcinol phthalein sodium
Uranine

CAS

518-47-8

Formula

C20H10Na2O5

Molecular Weight

376.28

EINECS

208-253-0

RTECS

LM5425000

RTECS Class

Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data

Merck

13,4185

Beilstein/Gmelin

3833041

Beilstein Reference

5-19-06-00456

Physical and Chemical Properties

Appearance

Orange-red to dark red powder. Odorless and almost tasteless.

Solubility in water

500 g/L

Melting Point

> 300

Density

1.601 g/cm3 (20 C)

pKa/pKb

2.2, 4.4, 6.7(at 25℃) (pKa)

Usage

Dye, ink pigment, in cosmetic products.

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid if irritation or symptoms occur.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Hazards Identification

Ingestion

In high doses may cause gastric irritation, nausea, vomiting, fever, skin rashes, and blood abnormalities including anemia.

Inhalation

Inhalation of dust may cause respiratory tract irritation.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

EC Safety Phrase

S 22 24/25

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Potential

This material is probably combustible.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions.

Stability and Reactivity

Disposal Code

3

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, carbon dioxide, sodium oxide.

Transport Information

HS Code

3204 12 00