Product Identification

Product Name

Betulin

Synonyms

3b,28-Dihydroxylup-20(29)-ene
Betulinic alcohol
Betulinol
Lup-20(29)-ene-3,28-diol, (3b)-
Lup-20(30)-ene-3b,28-diol

CAS

473-98-3

Formula

C30H50O2

Molecular Weight

442.73

EINECS

207-475-5

Merck

12,1237

Physical and Chemical Properties

Solubility in water

Insoluble

Melting Point

256 - 257

Vapor Pressure

4.3E-13 (25 C)

Density

1.156 g/cm3 (20 C)

pKa/pKb

14.83 (pKa)

Partition Coefficient

9.01

Usage

Exhibits anti-malarial, anti-inflamatory and anti-hiv activity as well as showing cytotoxicity towards a number of tumour cell lines.

Refractive Index

1.5186

First Aid Measures

Ingestion

Do not induce vomiting without medical advice.

Inhalation

Move to fresh air. Call a physician immediately.

Skin

Rinse immediately with plenty of water and seek medical advice.

Eyes

In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

Handling and Storage

Storage

Store at 4 C. Store under nitrogen.

Hazards Identification

Inhalation

May cause irritation of respiratory tract.

Skin

May cause allergic skin reaction.

Eyes

Causes irritation.

Ingestion

May be harmful if swallowed.

Exposure Controls/Personal Protection

Personal Protection

PVC or plastic material gloves. Safety glasses with side shields.

Exposure Effects

Chronic exposure may cause nausea and vomiting, higher exposure causes unconsciousness. Symptoms of overexposure may be headache, dizziness, tiredness, nausea and vomiting.

Fire Fighting Measures

Fire Fighting

Use dry chemical, CO2, water spray or alcohol foam. wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear

Accidental Release Measures

Small spills/leaks

Eliminate all ignition sources. Absorb and/or contain spill with inert material(s e.g., sand, vermiculite). Then place in appropriate container.

Stability and Reactivity

Stability

Stable under recommended storage conditions. Material is air and moisture sensitive.

Incompatibilities

Strong oxidizing agents.