Product Identification

Product Name

(25R)-5alpha-Spirostan-3beta-ol

Synonyms

(25R)-5a-Spirostan-3b-ol
Sulfur oxide
Sulfurous anhydride

CAS

7446-09-5

CAS

77-60-1

Formula

C27H44O3

Formula

O2(32)S

Molecular Weight

416.64

Molecular Weight

64.05

EINECS

201-041-9

EINECS

231-195-2

RTECS

WH1443500

RTECS

WS4550000

RTECS Class

Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector; Human Data; Primary Irritant

RTECS Class

Natural Product

Merck

12,9144

Merck

12,9575

Beilstein/Gmelin

1293741

Beilstein/Gmelin

1443 (G)

Beilstein Reference

6-19

EC Index Number

016-011-00-9

EC Class

Toxic; Corrosive

Physical and Chemical Properties

Appearance

A colorless gas with a choking or suffocating odor.

Solubility in water

8.5 g/100 mL (20 C)

Melting Point

-75.7

Melting Point

210 - 211

Boiling Point

-10.3

Boiling Point

517

Vapor Pressure

8E-13 (25 C)

Vapor Pressure

43.7 (-60 C)

Density

1.434 g/cm3 (20 C)

Heat Of Vaporization

25.4 kJ/mol

Heat Of Vaporization

90.8 kJ/mol

Usage

Preserving fruits, disinfectant in breweries & food factories.

Usage

Reduces serum cholesterol levels by inhibiting its absorption.

Vapor Density

2.2

Odor threshold

0.47 ppm

Refractive Index

1.3047 (20 C)

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Ingestion

Nausea, vomiting, and abdominal pain have been reported.

Ingestion

Seek medical assistance.

Inhalation

Vapors are extremely irritating and corrosive.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Inhalation

Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult. Effects may be delayed.

Skin

Direct contact with liquefied sulfur dioxide could cause frostbite injury.

Skin

Rewarming and a variety of topical treatments are indicated for frostbite injury. See main treatment section for more information.

Eyes

See Skin.

Eyes

Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Handling and Storage

Storage

Keep tightly closed. Store in a cool dry place.

Storage

Protect against physical damage, store outdoors or in a well ventilated area of noncombustible construction.

Handling

Containers of this material may be hazardous when emptied. Since emptied containers retain product residues (vapor, liquid, and/or solid), all hazard precautions given in the data sheet must be observed.

Hazards Identification

Inhalation

Material may be irritating to mucous membranes and upper respiratory tract.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Hazards

Containers may explode in heat of fire or they may rupture and release irritating toxic sulfur dioxide. Sulfur dioxide has explosive properties when it comes in contact with sodium hydride; potassium chlorate at elevated temperatures; ethanol; ether; zinc ethylsulfurinate at very cool temperatures (-15C); fluorine; chlorine trifluoride and chlorates. It will react with water or steam to produce toxic and corrosive fumes. When the liquid is heated it may release irritating, toxic sulfur dioxide gas.

UN (DOT)

1079

Exposure Controls/Personal Protection

Personal Protection

Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.

Personal Protection

Wear appropriate protective gloves, clothing and goggles.

Respirators

Wear positive pressure self-contained breathing apparatus (SCBA).

Exposure Effects

Maternal toxicity and embryotoxicity have been observed.

Exposure Effects

The chemical, physical, and toxicological properties of this product have not been thoroughly investigated. Exercise due care.

Exposure limit(s)

OSHA PEL: TWA 5 ppm (13 mg/m3) NIOSH REL: TWA 2 ppm (5 mg/m3) ST 5 ppm (13 mg/m3) NIOSH IDLH: 100 ppm

Poison Class

3

Fire Fighting Measures

Flash Point

266

Fire Fighting

Extinguish using Noncombustible. Use extinguishing media appropriate to surrounding fire conditions. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Fire Fighting

Wear self-contained breathing apparatus and full protective clothing. Move container from fire area. Stay away from ends of tanks. Cool containers that are exposed to flames with water from the side until well after the fire is out. Isolate area until gas has dispersed. Keep unnecessary people away.Not flammable. Extinguish fires with dry chemical, carbon dioxide, water spray, fog or foam.

Fire Potential

Nonflammable.

Accidental Release Measures

Small spills/leaks

Keep material out of water sources and sewers. Attempt to stop leak if without undue personnel hazard. Use water spray to knock-down vapors. Neutralize spilled material with crushed limestone, soda ash, or lime. Do not use water on material itself.

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Incompatibilities

Reacts exothermically with bases such as amines, amides, metal oxides, and hydroxides Reacts explosively with fluorine. Avoid ammonia, monocesium or monopotassium acetylide; dicesium monoxide; iron (II) oxide; tin oxide; lead (IV) oxide; chromium; manganese; molten sodium, powder aluminum and rubidium. Sulfur dioxide has explosive properties when it comes in contact with sodium hydride; potassium chlorate at elevated temperatures; ethanol; ether; zinc ethylsulfurinate at very cool temperatures (-15C); fluorine; chlorine trifluoride and chlorates. It will react with water or steam to produce toxic and corrosive fumes.

Stability

Stable at normal temperatures and pressures.

Stability

Stable.

Incompatibilities

Strong oxidizing agents.

Decomposition

Sulfur compounds.

Decomposition

Carbon monoxide, Carbon dioxide.

Transport Information

UN Number

1079

Hazard Class

2.3