Product Identification

Product Name

Erythromycin ethylsuccinate

Synonyms

Eritrocina
Erythromycin, 2'-(ethyl butanedioate)
Ethyl [(2R,3S,4R,6S)-4-dimethylamino-2-[[(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-14-ethyl-7,12,13-trihydroxy-4-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyl-oxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-1-oxacyclotetradec-6-yl]oxy]-6-methyl-oxan-3-yl] butanedioate
Monomycin
Paediathrocin
Succinic acid, monoester with erythromycin

CAS

1264-62-6

Formula

C43H75NO16

Molecular Weight

862.06

EINECS

215-033-8

RTECS

WM9800000

RTECS Class

Drug; Human Data

Beilstein/Gmelin

77638

Beilstein Reference

4-18-00-07416

Physical and Chemical Properties

Appearance

Crystals.

Solubility in water

Insoluble

Melting Point

109 - 110

pKa/pKb

6.42 (pKb)

Usage

Medication.

First Aid Measures

Ingestion

Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.

Inhalation

If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Handling and Storage

Storage

Keep in a cool, dry, well-ventilated area in a sealed container.

Handling

Keep container closed when not in use. Avoid contact. Follow label directions.

Exposure Controls/Personal Protection

Personal Protection

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.

Respirators

Where environmental controls are lacking or in an enclosed space, use a NIOSH/MSHA approved respirator for dust.

Exposure Effects

Allergic skin and respiratory reactions have been reported.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks

Ventilate area. Use protective eqiupment. Sweep or vacuum up. Do not creat dust. Place in a dry container for disposal. Clean spill area with water.

Stability and Reactivity

Stability

Stable.

Incompatibilities

Strong oxidizing agents.

Decomposition

None reported.