2-Hydroxy-2,2-diphenylacetic acid(76-93-7)
Product Identification
Product Name
2-Hydroxy-2,2-diphenylacetic acid
Synonyms
2-Hydroxy-2,2-diphenylacetic acid
a-Hydroxy-a-phenylbenzeneacetic acid
Diphenylglycolic acid
Diphenylhydroxyacetic acid
Hydroxydiphenylacetic acid
CAS
76-93-7
Formula
C14H12O3
Molecular Weight
228.25
EINECS
200-993-2
RTECS
DD2064000
RTECS Class
Drug
Merck
13,1080
Beilstein/Gmelin
521402
Beilstein Reference
4-10-00-01256
Physical and Chemical Properties
Appearance
White powder.
Solubility in water
Very soluble
Melting Point
150 - 152
Boiling Point
409
Vapor Pressure
2E-7 (25 C)
pKa/pKb
3.04 (pKa)
Partition Coefficient
3.03
Heat Of Vaporization
69.7 kJ/mol
Usage
Used in organic synthesis, as a base point for preparation of glycollate pharmaceuticals and some hallucinogenic drugs.
First Aid Measures
Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and Storage
Storage
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Exposure Controls/Personal Protection
Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Fire Fighting Measures
Flash Point
215
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.