Product Identification

Product Name

4-(Trifluoromethyl)aniline

Synonyms

(4-(Trifluoromethyl)phenyl)amine
4-(Trifluoromethyl)benzenamine
4-Aminobenzotrifluoride
p-Aminobenzotrifluoride

CAS

455-14-1

Formula

C7H6F3N

Molecular Weight

161.13

EINECS

207-236-5

RTECS

XU9260000

RTECS Class

Drug; Mutagen

Beilstein/Gmelin

1564853

Beilstein Reference

4-12-00-01982

EC Class

irritant

Physical and Chemical Properties

Appearance

Clear yellow liquid.

Solubility in water

Insoluble

Melting Point

3 - 8

Boiling Point

190

Vapor Pressure

0.55 (25 C)

Density

1.2901 g/cm3 (25 C)

pKa/pKb

11.23 (pKb)

Partition Coefficient

1.95

Heat Of Vaporization

42.6 kJ/mol

Vapor Density

5.6

Refractive Index

1.4851 (20 C)

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Wash clothing before reuse. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Hazards Identification

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.

Inhalation

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.

Skin

Causes skin irritation. The toxicological properties of this material have not been fully investigated.

Eyes

Causes eye irritation. The toxicological properties of this material have not been fully investigated.

EC Risk Phrase

R 23/24/25 33 36/38

EC Safety Phrase

S 26 36/37/39 45

UN (DOT)

3276

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Flash Point

86

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible Liquid. Extinguishing media: Use water spray to cool fire-exposed containers. Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Potential

Non-Combustible

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Provide ventilation.

Stability and Reactivity

Disposal Code

2

Incompatibilities

Oxidizing agents

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen fluoride, nitrogen.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

3276

Hazard Class

6.1

Packing Group

I; II; III

HS Code

2921 43 00