Product Identification

Product Name

(2alpha,6alpha,8alpha,9abeta)-Octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl-1H-indole-3-carboxylate

Synonyms

2-[4-(Thiophene-2-carbonyl)phenyl]propanoic acid
a-Methyl-p-(2-thenoyl)phenylacetic acid
Benzeneacetic acid, a-methyl-4-(2-thienylcarbonyl)-, (+/-)-
Maldocil
p-(2-Thenoyl)hydratropic acid

CAS

40828-46-4

Formula

C14H12O3S

Molecular Weight

260.31

EINECS

255-096-9

RTECS

MU6647000

RTECS Class

Drug; Reproductive Effector; Human Data; Primary Irritant

Merck

12,9180

Beilstein/Gmelin

1430606

Beilstein Reference

5-16-08-00403

Physical and Chemical Properties

Solubility in water

Soluble

Melting Point

124

Boiling Point

443

Vapor Pressure

1E-8 (25 C)

Density

1.37 g/cm3

pKa/pKb

4.07 (pKa)

Heat Of Vaporization

73.8 kJ/mol

Usage

Ophthalmic non-steroidal anti-flammatory.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.

Skin

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Hazards Identification

Inhalation

TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Effects of contact or inhalation may be delayed.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Ingestion

See Inhalation.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

23/24/25 40

EC Safety Phrase

22 36/37/39 45

UN (DOT)

2811

Exposure Controls/Personal Protection

Personal Protection

Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.

Respirators

Wear positive pressure self-contained breathing apparatus (SCBA).

Exposure Effects

Toxic. Toxic by inhalation, in contact with skin and if swallowed. Limited evidence of a carcinogenic effect. Target organ(s): Kidneys. Possible teratogen.

Fire Fighting Measures

Flash Point

222

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Fire Potential

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Decomposition

Carbon monoxide, Carbon dioxide, Sulfur oxides.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2811

Hazard Class

6.1

Packing Group

III