Product Identification

Product Name

p-2-Thiazolylsulfamoylsuccinanilic acid

Synonyms

2-(N4-Succinylsulfanilamido)thiazole
4'-(2-Thiazolylsulfamoyl)succinanilic acid
Butanoic acid, 4-oxo-4-[[4-[(2-thiazolylamino)sulfonyl]phenyl]amino]-
Cremosuxidine
Sulfenterone
Thiacyl

CAS

116-43-8

Formula

C13H13N3O5S2

Molecular Weight

355.4

EINECS

204-141-0

RTECS

WM4767000

RTECS Class

Drug; Natural Product

Merck

12,9046

Beilstein/Gmelin

349989

Beilstein Reference

4-27-00-04637

Physical and Chemical Properties

Solubility in water

Very soluble

Melting Point

187 - 193

pKa/pKb

4.51 (pKa)

Partition Coefficient

.74

Usage

Sulfonamid class antibiotic.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.

Skin

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Keep tightly closed.

Hazards Identification

Inhalation

May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.

Skin

May cause skin irritation. May be harmful if absorbed through the skin.

Eyes

May cause eye irritation.

Ingestion

May be harmful if swallowed.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

42/43

EC Safety Phrase

22 36/37 45

Exposure Controls/Personal Protection

Personal Protection

Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.

Exposure Effects

Harmful. May cause sensitization by inhalation and skin contact. Target organ(s): Kidneys. Blood.

Fire Fighting Measures

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Incompatibilities

Oxidizing agents.

Stability

Stable at normal temperatures and pressures.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Sulfur oxides.