Product Identification

Product Name

4-(Trifluoromethoxy)aniline

Synonyms

Benzenamine, 4-(trifluoromethoxy)-
p-Trifluoromethoxyaniline

CAS

461-82-5

Formula

C7H6F3NO

Molecular Weight

177.13

EINECS

207-317-5

Beilstein/Gmelin

2090209

Beilstein Reference

4-13-00-01030

Physical and Chemical Properties

Appearance

Clear very faint yellow liquid. Aniline odor.

Boiling Point

73

Density

1.3212 g/cm3 (25 C)

Refractive Index

1.46 (20 C)

First Aid Measures

Ingestion

Get medical aid. Wash mouth out with water.

Inhalation

Remove from exposure to fresh air immediately. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container.

Handling

Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Use only in a chemical fume hood.

Hazards Identification

Inhalation

Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.

Skin

Causes skin irritation. Harmful if absorbed through the skin.

Eyes

Causes eye irritation.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.

EC Risk Phrase

R 20/21/22 36/38

EC Safety Phrase

S 26 36/37/39

UN (DOT)

2810

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Absorption into the body leads to the formation of methemoglobin which in sufficient concentrations causes cyanosis. Onset may be delayed 2 to 4 hours or longer.

Fire Fighting Measures

Flash Point

80

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire. Combustible Liquid. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong acids - strong bases - strong oxidizing agents - strong reducing agents.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen fluoride.

Transport Information

UN Number

2810

HS Code

2922 29 00