Product Identification

Product Name

DL-Dithiothreitol

Synonyms

1,4-Dithio-DL-threitol
2,3-Butanediol, 1,4-dimercapto-, (2R,3R)-
DL-1,4-Dimercapto-2,3-dihydroxybutane
DL-1,4-Dithiothreitol
Sputolysin
threo-2,3-Dihydroxy-1,4-butanedithiol

CAS

27565-41-9

Formula

C4H10O2S2

Molecular Weight

154.24

EINECS

248-531-9

RTECS

XO8576500

RTECS Class

Mutagen

Beilstein/Gmelin

1719757

Beilstein Reference

3-01-00-02360

Physical and Chemical Properties

Appearance

White powder.

Solubility in water

Soluble

Melting Point

42

Boiling Point

125 - 130 (2 torr)

pKa/pKb

9.29 (pKa)

Usage

Reducing agent.

Vapor Density

5.3

First Aid Measures

Ingestion

Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a cool, dry place. Keep container closed when not in use. Refrigerator (approx 4 C).

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Hazards Identification

Ingestion

May cause irritation of the digestive tract.

Inhalation

May cause respiratory tract irritation.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Exposure Controls/Personal Protection

Personal Protection

Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Respirators

Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.

Fire Fighting Measures

Flash Point

> 110

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Stability

No data.

Incompatibilities

Oxidizing agents, reducing agents, bases, alkali metals.

Decomposition

Carbon monoxide, oxides of sulfur, carbon dioxide, hydrogen sulfide.