Product Identification

Product Name

Phenolsulfonephthalein

Synonyms

2,4,6-Trimethylheptan-4-ol
4-[3-(4-Hydroxyphenyl)-1,1-dioxobenzo[c]oxathiol-3-yl]phenol
Phenolsulfonphthalein
Sulfonphthal

CAS

143-74-8

CAS

60836-07-9

Formula

C10H22O

Formula

C19H14O5S

Molecular Weight

354.38

Molecular Weight

158.28

EINECS

205-609-7

RTECS

SJ7490000

RTECS Class

Mutagen

Merck

12,7397

Beilstein/Gmelin

326470

Beilstein/Gmelin

89331

Beilstein Reference

4-27-00-01269

Beilstein Reference

5-19-03-00457

Physical and Chemical Properties

Appearance

Bright to dark red, crystals or powder, odorless.

Solubility in water

Insoluble

Solubility in water

2 g/L

Melting Point

>300

Melting Point

162 - 163.5

Boiling Point

168 - 170 (0.1 torr)

Density

0.823 g/cm3 (21C)

pKa/pKb

7.9(at 25℃) (pKa)

Usage

Red dye, ph indicator, and diagnostic aid for determination of renal function.

Refractive Index

1.4334 (18 C)

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.

Ingestion

Seek medical assistance.

Inhalation

May be fatal. May cause irritatior or burns. Vapors may cause dizziness or suffocation.

Inhalation

Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult. Remove and isolate contaminated clothing and shoes.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.

Skin

See inhalation.

Skin

Get medical aid if irritation develops or persists. Flush skin with plenty of soap and water.

Skin

Remove and isolate contaminated clothing and shoes. In case of contact with substance, immediately flush with running water for at least 20 minutes. Wash skin with soap and water.

Eyes

See inhalation.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Eyes

In case of contact with substance, immediately flush with running water for at least 20 minutes.

Handling and Storage

Storage

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Storage

Store in a cool, dry place. Keep container closed when not in use.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Avoid ingestion and inhalation.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.

Ingestion

See inhalation.

Inhalation

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.

Skin

Dust may cause mechanical irritation.

Eyes

Dust may cause mechanical irritation.

Hazards

Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion and poison hazard indoors, outdoors or in sewers.

EC Risk Phrase

R 36/37/38

EC Safety Phrase

S 26 36

UN (DOT)

1986

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Personal Protection

Wear appropriate protective gloves, clothing and goggles.

Respirators

Wear positive pressure self-contained breathing apparatus (SCBA).

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Flash Point

>300

Fire Fighting

Use of water spray when fighting fire may be inefficient. Small Fires: Dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Large Fires: Water spray, fog or alcohol-resistant foam.

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Combustion generates toxic fumes. Extinguishing media: For small fires, use water spray, dry chemical, carbon dioxide or chemical foam.

Fire Potential

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.

Accidental Release Measures

Small spills/leaks

Make no contact with the spilled material. Fully encapsulating, vapor protective clothing should be worn for spills and leaks with no fire. ELIMINATE all ignition sources and ground all equipment. Stop leak if you can do it without risk. A vapor suppressing foam may be used to reduce vapors. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. Use clean non-sparking tools to collect absorbed material.

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Disposal Code

3

Stability

No data.

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide.

Combustion Products

Fire will produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

1986

Hazard Class

3

Packing Group

I; II; III

HS Code

2934 99 90