Product Identification

Product Name

2-Hydroxynitrobenzene

Synonyms

2-Hydroxynitrobenzene
2-Nitrophenol

CAS

88-75-5

Formula

C6H5NO3

Molecular Weight

139.11000000000001

EINECS

201-857-5

RTECS

SM2100000

RTECS Class

Other

Merck

12,6717

Beilstein/Gmelin

775403

Beilstein Reference

4-06-00-01246

EC Class

irritant

Physical and Chemical Properties

Appearance

Light yellow crystals with an aromatic odor.

Solubility in water

Soluble

Melting Point

43 - 45

Boiling Point

214.6

Vapor Pressure

0.093 (25 C)

Density

1.599 g/cm3 (20 C)

pKa/pKb

7.23 (pKa)

Partition Coefficient

1.77

Heat Of Vaporization

48.1 kJ/mol

Heat Of Combustion

-2871 kJ/mol

Usage

Acid-base indicator. Corrosion inhibitor for aluminium-copper alloy.

Vapor Density

1.5

Odor threshold

0.11-0.13 mg/m3

Refractive Index

1.5723 (50 C)

First Aid Measures

Ingestion

Do NOT induce vomiting. Allow the victim to rinse his mouth and then to drink 2-4 cupfuls of water, and seek medical advice.

Inhalation

Remove from exposure to fresh air immediately.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Handling and Storage

Storage

Tightly closed containers. Keep away from heat and water and from combustible organic or other readily oxidizable material.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation

Causes irritation to the respiratory tract. Symptoms may include coughing, shortness of breath. Can be a route of absorption by the body with symptoms like ingestion.

Skin

Causes irritation to skin. Symptoms include redness, itching, and pain. May be absorbed through the skin with possible systemic effects.

Eyes

Causes irritation, redness, and pain.

Ingestion

Toxic. Harmful if swallowed. Can cause formation of methemoglobin, resulting in cyanosis (blue lips), headaches, dizziness and collapse. Exposure to high concentrations may cause breathing trouble, a slow pulse, fall in blood pressure, convulsions and even death.

Hazards

When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.

EC Risk Phrase

R 20/22 33 36/37/38

EC Safety Phrase

S 26 36/37/39

UN (DOT)

1663

Exposure Controls/Personal Protection

Personal Protection

Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact. Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible.

Respirators

For conditions of use where exposure to the dust or mist is apparent, a half-face dust/mist respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.

Exposure Effects

Chronic exposure may damage the liver and kidneys.

Poison Class

2

Fire Fighting Measures

Flash Point

97

Autoignition

550

Fire Fighting

Wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode. Extinguishing agents: water, foam, dry chemical, carbon dioxide. Do not allow water runoff to enter sewers or waterways.

Fire Potential

Combustible solid.

Accidental Release Measures

Small spills/leaks

Sweep up, then place into a suitable container for disposal.

Stability and Reactivity

Disposal Code

3

Incompatibilities

Halogen acids and strong oxidizing agents. In liquid/molten state, reacts violently with potassium hydroxide.

Stability

Stable under normal temperatures and pressures.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Combustion Products

Toxic and irritating fumes of unburned material and oxides of nitrogen can form in fire.

Transport Information

UN Number

1663

Hazard Class

6.1

Packing Group

III

HS Code

2908 90 00