Product Identification

Product Name

HMDI

Synonyms

1,6-Diisocyanatohexane
1,6-Hexamethylene diisocyanate
Hexamethylene di-isocyanate
Hexamethylene-1,6-diisocyanate
HMDI

CAS

822-06-0

Formula

C8H12N2O2

Molecular Weight

168.2

EINECS

212-485-8

RTECS

MO1740000

RTECS Class

Agricultural Chemical and Pesticide

Beilstein/Gmelin

956709

Beilstein Reference

4-04-00-01349

EC Index Number

615-011-00-1

EC Class

Toxic; Irritant; Sensitising

Physical and Chemical Properties

Appearance

Colorless to slightly yellow liquid with a sharp, pungent odor.

Solubility in water

Reacts

Melting Point

-67

Boiling Point

255

Vapor Pressure

.05

Density

0.972 g/cm3 (15 C)

Usage

Component of polyurethane elastomers, coatings.

Vapor Density

5.81

Saturation Concentration

Approximately 66 ppm at 25 C (calculated)

Odor threshold

0.001 ppm

Refractive Index

1.45067 (20 C)

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Do NOT allow victim to rub or keep eyes closed.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 C). Store protected from moisture.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Do not allow contact with water. Keep from contact with moist air and steam.

Hazards Identification

Inhalation

May cause asthmatic attacks due to allergic sensitization of the respiratory tract. Causes irritation of mucous membrane. At high concentrations, isocyanates affect mucous membranes of the respiratory tract and may lead to fatal pulmonary edema. Exposure to low and often even unmeasurable isocyanate concentration results in sensitization. Symptoms of exposure include: increased secretions, cough, pain or respiration, Symptoms of initial exposure may include nocturnal dyspnea with nocturnal cough with progression to asthmatic bronchitis.

Skin

Causes severe skin irritation. Harmful if absorbed through the skin. If absorbed, causes symptoms similar to those of ingestion.

Eyes

Causes severe eye irritation. Lachrymator. Vapors may cause reversible corneal epithelial edema with impairing of vision.

Ingestion

May cause irritation of the digestive tract. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed.

Hazards

Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.

EC Risk Phrase

R 23 36/37/38 42/43

EC Safety Phrase

S 26 28.1 38 45

UN (DOT)

2281

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Chronic inhalation may cause effects similar to those of acute inhalation. Repeated exposure may cause allergic respiratory reaction (asthma). Effects may be delayed. Prolonged or repeated exposure may cause lung irritation, chest pain, and pulmonary edema. Chronic overexposure to isocyanates has been reported to cause lung damage, including decreased lung fuction, which may be permanent.

Exposure limit(s)

NOISH: 0.005 ppm TWA; 0.035 mg/m3 TWA

Poison Class

2

Fire Fighting Measures

Flash Point

130

Autoignition

454

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Fire or excessive heat may result in violent rupture of the container due to bulk polymerization. Extinguishing media: Use extinguishing media most appropriate for the surrounding fire. Do NOT get water inside containers. For large fires, use water spray, fog or alcohol-resistant foam. Do NOT use straight streams of water. For small fires, use carbon dioxide, dry chemical, dry sand, or alcohol-resistant foam. Most foams will react with the material and release corrosive/toxic gases. Cool containers with flooding quantities of water until well after fire is out.

Upper exp. limit

9.5

Lower exp. limit

.9

Fire Potential

May burn but does not ignite readily.

Accidental Release Measures

Small spills/leaks

Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation. Do not get water on spilled substances or inside containers. Cover with dry earth, dry sand, or other non-combustible material followed with plastic sheet to minimize spreading and contact with water.

Stability and Reactivity

Disposal Code

9

Stability

Stable at room temperature in closed containers under normal storage and handling conditions. Polymerization may occur upon heating.

Incompatibilities

Strong oxidizing agents, strong bases, alcohols, amines, heat, moisture, water, carboxylic acids, organotin catalysts.

Decomposition

Hydrogen cyanide, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Combustion Products

Fire will produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2281

Hazard Class

6.1

Packing Group

II

HS Code

2929 10 90