Product Identification

Product Name

3-Aminotoluene

Synonyms

3-Aminophenylmethane
3-Aminotoluene
Butanedioic anhydride
Dihydro-2,5-furandione
m-Methylaniline
Oxolane-2,5-dione
Succinyl oxide
Tetrahydro-2,5-dioxofuran
Tetrahydro-2,5-furandione

CAS

108-30-5

CAS

108-44-1

Formula

C4H4O3

Formula

C7H9N

Molecular Weight

100.07

Molecular Weight

107.16

EINECS

203-570-0

EINECS

203-583-1

RTECS

WN0875000

RTECS

XU2800000

RTECS Class

Primary Irritant

RTECS Class

Tumorigen; Mutagen; Reproductive Effector; Primary Irritant

Merck

12,9039

Merck

12,9674

Beilstein/Gmelin

108441

Beilstein/Gmelin

635944

Beilstein Reference

4-12-00-01813

Beilstein Reference

5-17-11-00006

EC Index Number

607-103-00-5

EC Index Number

612-024-00-4

EC Class

Irritant

EC Class

Toxic; Danger of cumulative effects; Dangerous for the Environment

Physical and Chemical Properties

Appearance

Colorless needles or white crystalline solid.

Appearance

Colorless to light yellow liquid, aromatic, aniline-like odor.

Solubility in water

20 g/L

Melting Point

-30

Boiling Point

203

Boiling Point

261

Vapor Pressure

.3

Vapor Pressure

0.012 (25 C)

Density

0.98444 g/cm3

Density

1.503 g/cm3

pKa/pKb

9.30 (pKb)

Partition Coefficient

-1.31

Partition Coefficient

1.4

Heat Of Vaporization

45.64 kJ/mol

Heat Of Vaporization

49.9 kJ/mol

Heat Of Combustion

-4043 kJ/mol

Heat Of Combustion

-1537 kJ/mol

Usage

Acidulant in processed foods.

Usage

Manufacture dyes and other organic chemicals.

Saturation Concentration

1316 ppm (0.1%) at 41 C (calculated)

Vapor Density

3.7

Refractive Index

1.56293 (15 C)

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.

Ingestion

May cause irritation of the digestive tract. May be harmful if swallowed.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.

Inhalation

Causes respiratory tract irritation. May cause allergic respiratory reaction.

Skin

Causes skin irritation.

Skin

Get medical aid if irritation develops or persists. Wash clothing before reuse. Flush skin with plenty of soap and water.

Skin

Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Eyes

Causes eye irritation.

Handling and Storage

Storage

Keep away from sources of ignition. Do not store in direct sunlight. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Storage

Store in a cool, dry place. Keep container closed when not in use.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid contact with heat, sparks and flame. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Hazards Identification

Inhalation

Causes cyanosis, characterized by bluish-colored skin. May cause anoxia, characterized by weakness, headache, dizziness, confusion, cyanosis, weak and irregular heart beat, collapse, unconsciousness, convulsions, coma and death. May cause methemoglobinemia, cyanosis, convulsions, tachycardia, dyspnea, and death. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown blood.

Skin

Causes skin irritation. May be absorbed through the skin. Causes symptoms similar to those of inhalation. Excessive drying of the skin may result form repeated or prolonged contact.

Eyes

Causes severe eye irritation. May cause severe eye burns.

Ingestion

Harmful if swallowed. May cause irritation of the digestive tract. May cause effects similar to those for inhalation exposure. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood. Overexposure may cause methemoglobinemia.

Hazards

When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.

EC Risk Phrase

R 23/24/25 33 50

EC Risk Phrase

R 36/37

EC Safety Phrase

S 25

EC Safety Phrase

S 28 36/37 45 61

UN (DOT)

1708

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Personal Protection

Eyes: Wear safety glasses and chemical goggles if splashing is possible. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

May cause cancer according to animal studies.

Exposure Effects

Chronic inhalation may cause effects similar to those of acute inhalation. May cause kidney injury. Absorption into the body leads to the formation of methemoglobin which in sufficient concentrations causes cyanosis. May cause anemia and other blood cell abnormalities. Contact with the skin may cause cutaneous lesions.

Exposure limit(s)

TLV: 2 ppm; 8.8 mg/m3 (as TWA) (skin) (ACGIH 1994-1995). NIOSH REL: See Appendix D

Poison Class

5

Fire Fighting Measures

Flash Point

122

Flash Point

90

Autoignition

> 500

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible Liquid. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Cool containers with flooding quantities of water until well after fire is out.

Upper exp. limit

20.3

Upper exp. limit

7.6

Lower exp. limit

1.2

Lower exp. limit

2.7

Fire Potential

Flammable when exposed to heat or flame.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Disposal Code

4

Disposal Code

9

Stability

Stable under normal temperatures and pressures.

Stability

Stable under normal temperatures and pressures. Substance undergoes color change upon exposure to light and air.

Incompatibilities

Strong oxidizing agents - strong acids - air - light.

Incompatibilities

Strong oxidizing agents, acids, bases, alcohols, amines, moist air or water.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Combustion Products

Toxic oxides of nitrogen and flammable vapors may form in fire.

Transport Information

UN Number

1708

Hazard Class

6.1

Packing Group

II

HS Code

2917 19 90

HS Code

2921 43 00