Product Identification

Product Name

5-Fluoro-5′-deoxyuridine

Synonyms

(+)-5-Fluoro-5'-deoxyuridine
2,4(1H,3H)-Pyrimidinedione, 1-(5-deoxy-b-D-ribofuranosyl)-5-fluoro-
5'-Deoxy-5-fluorouridine
5-Fluoro-5'-deoxyuridine
5-Fluorodesoxyuridine

CAS

3094-09-5

Formula

C9H11FN2O5

Molecular Weight

246.2

EINECS

221-440-1

RTECS

YU7526000

RTECS Class

Drug; Mutagen; Reproductive Effector

Merck

13,3471

Beilstein/Gmelin

890191

Beilstein Reference

6-24

Physical and Chemical Properties

Solubility in water

Soluble

Melting Point

186 - 188

pKa/pKb

5.34 (pKb)

Usage

Medication used in chemotherapy.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Keep tightly closed.

Hazards Identification

Inhalation

May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.

Skin

May cause skin irritation. May be harmful if absorbed through the skin.

Eyes

May cause eye irritation.

Ingestion

May be harmful if swallowed.

Hazards

Emits toxic fumes under fire conditions.

Exposure Controls/Personal Protection

Personal Protection

Protective gloves. Chemical safety goggles.

Respirators

Wear dust mask.

Exposure Effects

Avoid contact and inhalation. Target organ(s): Nerves. Cardiovascular system.

Fire Fighting Measures

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen fluoride.