Product Identification

Product Name

2-Nitropropane

Synonyms

Dimethylnitromethane
Isonitropropane
sec-Nitropropane

CAS

79-46-9

Formula

C3H7NO2

Molecular Weight

89.09

EINECS

201-209-1

RTECS

TZ5250000

RTECS Class

Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector; Human Data

Merck

12,6725

Beilstein/Gmelin

1740684

Beilstein Reference

4-01-00-00230

EC Index Number

609-002-00-1

EC Class

Flammable; Carcinogenic Category 2; Harmful

Physical and Chemical Properties

Appearance

Clear, colorless, oily liquid with a pleasant, mild odor described as fruity.

Solubility in water

20 g/L

Melting Point

-91

Boiling Point

120.3

Vapor Pressure

13 (20 C)

Density

0.9927 g/cm3 (20 C)

pKa/pKb

8.44 (pKa)

Partition Coefficient

.68

Heat Of Vaporization

41.0 kJ/mol

Heat Of Combustion

-1996 kJ/mol

Usage

Chemical synthesis, rocket propellant, gasoline additive.

Vapor Density

3.06

Saturation Concentration

1.7 percent (20 C)

Odor threshold

25 ppm

Refractive Index

1.3944 (20 C)

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Skin

Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Remove contaminated clothing and shoes.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Do not store near combustible materials. Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Do not breathe dust, vapor, mist, or gas. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Hazards Identification

Inhalation

Breathing of vapor or mist is possible. Breathing small amounts of this material during normal handling is not likely to cause harmful effects. Breathing large amounts may be harmful 2-Nitropropane has been linked with several work-related deaths from irreversible liver damage caused when 2-nitropropane-containing products were applied in confined or enclosed spaces without use of adequate respiratory protection or adequate ventilation.

Skin

May cause mild skin irritation. Symptoms may include redness and burning of skin.

Eyes

May cause mild eye irritation. Symptoms include stinging tearing, and redness.

Ingestion

Swallowing small amounts of this material during normal handling is not likely to cause harmful effects. Swallowing large amounts may be harmful.

Hazards

Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.

EC Risk Phrase

R 45 10 20/22

EC Safety Phrase

S 53 45

UN (DOT)

2608

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Signs and symptoms of exposure to this material through breathing, swallowing, and/or passage of the material through the skin may include: stomach or intestinal upset (nausea, vomiting, diarrhea irritation (nose, throat, airways), central nervous system depression (dizziness, drowsiness, weakness, fatigue, nausea, headache, unconsciousness), and death. Overexposure to this material (or its components) has been suggested as a cause of the following effects in laboratory animals: blood abnormalities, liver abnormalities, kidney damage, lung damage, brain damage.

Exposure limit(s)

TLV: 10 ppm; 36 mg/m3 A2 (as TWA) (ACGIH 994-1995). OSHA PEL: TWA 25 ppm (90 mg/m3) NIOSH REL: Ca See Appendix A NIOSH IDLH: Potential occupational carcinogen 100 ppm

Poison Class

1*

Fire Fighting Measures

Flash Point

26

Autoignition

425

Fire Fighting

Wear a self-contained breathing apparatus with a full facepiece operated in the positive pressure demand mode with appropriate turn-out gear and chemical resistant personal protective equipment, Extinguishing media include regular foam, carbon dioxide, dry chemical

Upper exp. limit

11

Lower exp. limit

2.6

Fire Potential

Moderately flammable. Combustion with moderate heating.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. A vapor suppressing foam may be used to reduce vapors.

Stability and Reactivity

Disposal Code

9

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents, strong acids, strong bases, copper, copper alloys, chlorosulfonic acid, oleum, lead, amines + heavy metal oxides (e.g. mercury oxide or silver oxide), carbon + hopcalite (catalyst consisting of coprecipitated copper (II) oxide and manganese (IV) oxide), stong alkalies.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Combustion Products

Toxic oxides of nitrogen may form in fire.

Transport Information

UN Number

2608

Hazard Class

3

Packing Group

III

HS Code

2904 20 00