Product Identification

Product Name

2-Aminothiazole

Synonyms

2-Amino-1,3-thiazole
2-Aminothiazole
Abadol
Abadole
Aminothiazole

CAS

96-50-4

Formula

C3H4N2S

Molecular Weight

100.14

EINECS

202-511-6

RTECS

XJ2100000

RTECS Class

Drug; Mutagen

Merck

13,479

Beilstein/Gmelin

105738

Beilstein Reference

4-27-00-04574

EC Class

harmful

Physical and Chemical Properties

Appearance

Light brown crystals or brown granular solid.

Solubility in water

Soluble

Melting Point

86 - 89

Boiling Point

216

Vapor Pressure

0.14 (25 C)

Density

1.5 g/cm3

pKa/pKb

8.58 (pKb)

Partition Coefficient

.38

Heat Of Vaporization

45.3 kJ/mol

Usage

Can be used as a thyroid inhibitor in the treatment of hyperthyroidism and it has antibacterial activity.

Vapor Density

3.5

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Hormones and antibiotics room. Refrigerator (approx 4 C).

Handling

Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Do not breathe dust, vapor, mist, or gas. Keep container tightly closed. Do not ingest or inhale.

Hazards Identification

Inhalation

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Ingestion

Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea.

Hazards

Contact with metals may evolve flammable hydrogen gas.

EC Risk Phrase

R 22 36/37/38

EC Safety Phrase

S 26 36/37/39

UN (DOT)

1759

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Laboratory experiments have resulted in mutagenic effects.

Fire Fighting Measures

Flash Point

85

Autoignition

600

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Potential

This material is probably combustible.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Disposal Code

3

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents, strong acids, acid chlorides, acid anhydrides, nitric acid, sulfuric acid.

Decomposition

Nitrogen oxides, carbon monoxide, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

1759

Hazard Class

8

Packing Group

I; II; III

HS Code

2934 10 00