Product Identification

Product Name

[2-(17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] propanoate

Synonyms

[2-(17-Ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] propanoate
Dermatop
Prednisolone 17-(ethyl carbonate) 21-propionate
Prednitop
Pregna-1,4-diene-3,20-dione, 17-[(ethoxycarbonyl)oxy]-11-hydroxy-21-(1-oxopropoxy)-, (11b)-
Regenit

CAS

73771-04-7

Formula

C27H36O8

Molecular Weight

488.58

EINECS

277-590-3

Merck

12,7899

Physical and Chemical Properties

Solubility in water

1.0 mg/L (25 C)

Melting Point

110 - 112

Boiling Point

641

Vapor Pressure

4.1E-19 (25 C)

Density

1.25 g/cm3 (20 C)

pKa/pKb

14.08 (pKa)

Partition Coefficient

4.02 (25 C)

Heat Of Vaporization

108/4 kJ/mol

Usage

Topical corticosteroid drug. It is similar in potency to hydrocortisone. Compared to other topical corticosteroids, like betamethasone, repeated prednicarbate use does not cause skin atrophy as quickly.

Fire Fighting Measures

Flash Point

209