Product Identification

Product Name

9-(3-Methylbut-2-enyloxy)-7H-furo[3,2-g]chromen-7-one

Synonyms

6-Hydroxy-7-(3-methyl-2-butenyloxy)-5-benzofuranacrylic acid omega-lactone
8-Isoamylenoxypsoralen
8-Isopentenyloxypsoralene
9-(3-Methylbut-2-enyloxy)-7H-furo[3,2-g]chromen-7-one
Ammidin
Marmelosin

CAS

482-44-0

Formula

C16H14O4

Molecular Weight

270.27999999999997

EINECS

207-581-1

RTECS

LV1575000

RTECS Class

Mutagen

Merck

12,4960

Beilstein/Gmelin

249728

Beilstein Reference

5-19-06-00016

Physical and Chemical Properties

Appearance

Prisms from ether; long fine needles from hot water.

Solubility in water

practically insoluble in cold water

Melting Point

103

Usage

Aromatic agent.

First Aid Measures

Ingestion

Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.

Inhalation

If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.

Skin

Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.

Eyes

Uv absorbing wrap should be used around sunglasses for 24 hours after methoxsalen ingestions. This decreases the potential for cataract formation.

Handling and Storage

Storage

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Skin

Erythema and bizarre pigmentation have been seen. Superficial and deep second-degree burns to the skin have been reported following puva therapy. At therapeutic doses, 8-mop will cause more dermal reactions than 5-mop.

Ingestion

Nausea and abdominal pain have occurred.

Exposure Controls/Personal Protection

Personal Protection

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.

Respirators

Use NIOSH/MSHA approved respirator appropriate for exposure of concern.

Exposure Effects

dizziness, depression, and headache have been reported with use, as have nervousness and insomnia. Seizures have been reported in animal studies.

Poison Class

3

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks

Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.

Stability and Reactivity

Stability

No data.

Incompatibilities

Strong oxidizing agents.