Product Identification

Product Name

1-Bromo-2-nitrobenzene

Synonyms

2-Bromo-1-nitrobenzene
Benzene, 1-bromo-2-nitro-
o-Bromonitrobenzene
o-Nitrobromobenzene
o-Nitrophenyl bromide

CAS

577-19-5

Formula

C6H4BrNO2

Molecular Weight

202.01

EINECS

209-409-0

RTECS

CY9040450

RTECS Class

Mutagen

Beilstein/Gmelin

2044109

Beilstein Reference

4-05-00-00728

Physical and Chemical Properties

Appearance

Yellow solid.

Solubility in water

Insoluble

Melting Point

39 - 42

Boiling Point

261

Density

1.62 g/cm3 (20 C)

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Wash clothing before reuse.

Hazards Identification

Inhalation

Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Can produce delayed pulmonary edema.

Skin

Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. May be absorbed through the skin.

Eyes

Causes eye irritation.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. Effects may be delayed 2 to 4 hours. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood.

Hazards

Containers may explode when heated.

EC Risk Phrase

R 20/21/22 33 36/38

EC Safety Phrase

S 26 36/37/39

UN (DOT)

2732

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Effects may be delayed. Laboratory experiments have resulted in mutagenic effects.

Fire Fighting Measures

Flash Point

112

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Potential

Combustible material: may burn but does not ignite readily.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Disposal Code

3

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Incompatibilities

Strong bases, strong oxidizing agents.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, bromine.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2732

Hazard Class

6.1

Packing Group

III

HS Code

2904 90 85