Product Identification

Product Name

2,4-Dichloro-5-methylpyrimidine

Synonyms

5-Methyl-2,4-dichloropyrimidine
NSC 37532

CAS

1780-31-0

Formula

C5H4Cl2N2

Molecular Weight

163.01

EINECS

217-227-8

Physical and Chemical Properties

Solubility in water

3.9 g/L (25 C)

Melting Point

26

Boiling Point

235

Vapor Pressure

0.079 (25 C)

Density

1.39 g/cm3 (25 C)

pKa/pKb

16.44 (pKa)

Partition Coefficient

1.62

Heat Of Vaporization

45.25 kJ/mol

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Keep container tightly closed.

Hazards Identification

Inhalation

Material is extremely destructive to the tissue of the mucous membranes and upper respiratory tract. May be harmful if inhaled.

Skin

Causes burns. May be harmful if absorbed through the skin.

Eyes

Causes burns. Lachrymator.

Ingestion

May be harmful if swallowed.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

34

EC Safety Phrase

26 36/37/39 45

UN (DOT)

3261

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.

Respirators

Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator.

Exposure Effects

Inhalation may result in spasm, inflammation and edema of the larynx and bronchi, chemical pneumonitis, and pulmonary edema. Symptoms of exposure may include burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting. Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin.

Fire Fighting Measures

Flash Point

119

Fire Fighting

Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents, Strong acids.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas.

Transport Information

UN Number

3261

Hazard Class

8

Packing Group

II