Product Identification

Product Name

N-Acetyl-L-glutamic acid

Synonyms

(2S)-2-Acetamidopentanedioic acid
L-Glutamic acid, N-acetyl-
L-N-Acetylglutamic acid
N-Acetyl-L-glutamic acid
N-Acetyl-S-glutamic acid
NAcGlu

CAS

1188-37-0

Formula

C7H11NO5

Molecular Weight

189.17

EINECS

214-708-4

RTECS

LZ9725000

RTECS Class

Other

Beilstein/Gmelin

1727473

Beilstein Reference

4-04-00-03047

Physical and Chemical Properties

Appearance

White solid.

Solubility in water

Very soluble

Melting Point

191 - 194

Boiling Point

425

Density

1.43 g/cm3

pKa/pKb

3.51 (pKa)

Partition Coefficient

-1.46

Usage

Activates carbamoyl phosphate synthase in the urea cycle.

First Aid Measures

Ingestion

Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a cool, dry place. Keep container closed when not in use. Refrigerator (approx 4 C).

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Hazards Identification

Ingestion

Ingestion of large amounts may cause gastrointestinal irritation. The toxicological properties of this substance have not been fully investigated.

Inhalation

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Poison Class

4 (Substances and products that must be considered harmful)

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidants.

Decomposition

Irritating and toxic fumes and gases.

Transport Information

HS Code

2924 19 00