Product Identification

Product Name

7-Nitro-1H-indazole

Synonyms

7-Nitro-1H-indazole
7-Nitroindazole

CAS

2942-42-9

Formula

C7H5N3O2

Molecular Weight

163.13

EINECS

220-934-4

RTECS

NK7962200

RTECS Class

Mutagen

Beilstein/Gmelin

6809

Beilstein Reference

5-23-06-00189

Physical and Chemical Properties

Appearance

Odorless orange-yellow powde.r

Melting Point

190

Density

1.56 g/cm3 (293 C)

Partition Coefficient

3.96

Usage

An inhibitor of nitric oxide synthase; exhibits anti-nociceptive activity without increasing blood pressure.

First Aid Measures

Ingestion

Get medical aid. Wash mouth out with water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Deep freeze (below -20 C).

Handling

Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.

Hazards Identification

Ingestion

Harmful if swallowed. Ingestion of 1 to 30 grams of soluble silver salts can cause argyria, which is characterized by permanent blue-gray pigmentation of the skin, mucous membranes, and eyes. Pigmentation is permanent.

Inhalation

Harmful if inhaled.

Skin

Harmful if absorbed through the skin.

Eyes

May cause eye irritation.

EC Risk Phrase

R 40

EC Safety Phrase

S 22 36/37

Exposure Controls/Personal Protection

Personal Protection

Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Stability

No data.

Incompatibilities

Strong oxidizing agents, strong acids.

Decomposition

Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide.