Product Identification

Product Name

3-[(2S)-1-Methylpyrrolidin-2-yl]pyridine ditartrate

Synonyms

Nicotine acid tartrate
Nicotine dihydrogen ditartrate
Nicotine ditartrate

CAS

65-31-6

Formula

C18H26N2O12

Molecular Weight

462.46

EINECS

200-607-2

RTECS

QT0350000

RTECS Class

Drug; Reproductive Effector

Beilstein/Gmelin

4284712

Physical and Chemical Properties

Appearance

A reddish white crystalline solid.

Solubility in water

Very Soluble

Melting Point

88-89

Usage

Used in a medicine as a drug which counteracts the effect of tetanus and strychnine poisoning.

First Aid Measures

Ingestion

Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.

Skin

May cause skin irritation. May be absorbed through the skin.

Eyes

May cause eye irritation.

Ingestion

Harmful if swallowed. May cause irritation of the digestive tract. May cause central nervous system stimulation.

Hazards

Containers may explode when heated. Runoff may pollute waterways.

UN (DOT)

1659

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Reproductive effects have been reported in animals. Repeated or prolonged exposure may cause CNS stimulation.

Fire Fighting Measures

Autoignition

244

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use extinguishing media appropriate to the surrounding fire. Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Extinguishing media: Substance is noncombustible; use agent most appropriate to extinguish surrounding fire. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use water spray, fog or regular foam.

Fire Potential

Moderate when exposed to heat or flame.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Incompatibilities

Oxidizing agents.

Stability

Stable under normal temperatures and pressures.

Decomposition

Carbon monoxide, oxides of nitrogen, irritating and toxic fumes and gases, carbon dioxide.

Combustion Products

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Transport Information

UN Number

1659

Hazard Class

6.1

Packing Group

II