Product Identification

Product Name

1-Hydroxy-9,10-anthracenedione

Synonyms

1-Hydroxy-9,10-anthracenedione
1-Hydroxy-9,10-anthraquinone
1-Hydroxyanthracene-9,10-dione

CAS

129-43-1

Formula

C14H8O3

Molecular Weight

224.22

EINECS

204-946-7

RTECS

CB7178000

RTECS Class

Tumorigen; Mutagen; Primary Irritant

Beilstein/Gmelin

1912751

Beilstein Reference

4-08-00-02586

Physical and Chemical Properties

Appearance

Red-orange to fine yellow crystals

Solubility in water

0.5 mg/L (25 C)

Melting Point

192-194

Boiling Point

415

Vapor Pressure

1.8E-7 (25 C)

pKa/pKb

7.15 (pKa)

Heat Of Vaporization

69.4 kJ/mol

Usage

1-Hydroxyanthraquinone can be used as an intermediate in the production of dyes and drugs.

First Aid Measures

Ingestion

Rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool.

Inhalation

Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary. Monitor for shock and treat if necessary. Anticipate seizures and treat if necessary

Skin

Cover skin burns with dry sterile dressings after decontamination.

Eyes

Flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport to medical facility.

Handling and Storage

Storage

Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required need to be carried. Carcinogens should be kept in only one section of storage cabinet, explosion-proof refrigerator or freezer that bears appropriate label.

Hazards Identification

Inhalation

Causes irritation.

Skin

Causes irritation.

Eyes

Causes irritation.

Exposure Controls/Personal Protection

Personal Protection

During manufacture, wear protective suits (preferably disposable, one-piece and close-fitting at ankles and wrists), gloves hair covering and overshoes. In s chemical laboratory, gloves and gowns should always be worn. However, gloves should not be assumed to provide full protection.

Respirators

Carefully fitted masks or respirators may be necessary when working with particulates or gases.

Fire Fighting Measures

Flash Point

219

Accidental Release Measures

Small spills/leaks

Material should be collected and placed or collected in proper containers for disposal. The lid should be secured and the bottles properly labelled. Once filled, bottles should be placed in plastic bag, so that outer surface is not contaminated

Stability and Reactivity

Decomposition

Emits acrid smoke and fumes when heated to decomposition.