Product Identification

Product Name

4-Methoxy-N,N'-bis(3-pyridinylmethyl)-1,3-benzenedicarboxamide

Synonyms

-1,3-Benzenedicarboxamide, N,N'-bis(3-pyridinylmethyl)-4-methoxy
4-Methoxy-N,N'-bis(3-pyridylmethyl)isophthalamide
Isophthalamide, 4-methoxy-N,N'-bis(3-pyridylmethyl)-
N,N'-Bis(3-picolyl)-4-methoxyisophthalamide
N,N'-Bis(3-pyridinylmethyl)-4-methoxy-1,3-benzenedicarboxamide

CAS

32828-81-2

Formula

C21H20N4O3

Molecular Weight

376.41

EINECS

251-245-7

RTECS

CZ2235500

RTECS Class

Drug

Merck

12,7560

Beilstein/Gmelin

499268

Beilstein Reference

5-22-09-00319

Physical and Chemical Properties

Solubility in water

Insoluble

Melting Point

124

Boiling Point

668

Vapor Pressure

1E-17 (25 C)

pKa/pKb

9.03 (pKb)

Heat Of Vaporization

98.2 kJ/mol

Usage

Cardiovascular protection in diabetics. Thromboxane a2 inhibitor.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Keep tightly closed.

Hazards Identification

Inhalation

May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.

Skin

May cause skin irritation. May be harmful if absorbed through the skin.

Eyes

May cause eye irritation.

Ingestion

May be harmful if swallowed.

Hazards

Emits toxic fumes under fire conditions.

Exposure Controls/Personal Protection

Personal Protection

Protective gloves. Chemical safety goggles.

Respirators

Wear dust mask.

Exposure Effects

Avoid contact and inhalation.

Fire Fighting Measures

Flash Point

358

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides.