Product Identification

Product Name

p-Fluorophenylacetic acid

Synonyms

(4-Fluorophenyl)acetic acid
(p-Fluorophenyl)acetic acid
2-(4-Fluorophenyl)acetic acid
Ba 2821

CAS

405-50-5

Formula

C8H7FO2

Molecular Weight

154.13999999999999

EINECS

206-972-4

Merck

13,4204

Beilstein/Gmelin

972145

Beilstein Reference

4-09-00-01672

Physical and Chemical Properties

Appearance

White to pale yellow solid. Characteristic odor.

Solubility in water

Very soluble

Melting Point

84 - 85

Boiling Point

264

Vapor Pressure

0.005 (25 C)

pKa/pKb

4.26 (pKa)

Partition Coefficient

1.456

Heat Of Vaporization

53.2 kJ/mol

Usage

Intermediate in the production of fluorinated anesthetics.

Vapor Density

5.3

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid. Wash mouth out with water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.

Inhalation

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.

Skin

May cause skin irritation. The toxicological properties of this material have not been fully investigated.

Eyes

May cause eye irritation. The toxicological properties of this material have not been fully investigated.

EC Risk Phrase

R 36/37/38

EC Safety Phrase

S 26 36

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Flash Point

114

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Disposal Code

4

Incompatibilities

Oxidizing agents.

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen fluoride.

Transport Information

HS Code

2916 39 00