Product Identification

Product Name

Ampyrone

Synonyms

1,2-Dihydro-1,5-dimethyl-2-phenyl-4-amino-3H-pyrazol-3-one
1-Phenyl-2,3-dimethyl-4-amino-5-pyrazolone
3H-Pyrazol-3-one, 4-amino-1,2-dihydro-1,5-dimethyl-2-phenyl-
4-Amino-1,5-dimethyl-2-phenyl-3-pyrazolone
4-Amino-2,3-dimethyl-1-phenyl-5-pyrazolone
Metapirazone

CAS

83-07-8

Formula

C11H13N3O

Molecular Weight

203.25

EINECS

201-452-3

RTECS

CD2480000

RTECS Class

Drug; Mutagen

Merck

13,596

Beilstein/Gmelin

181635

Beilstein Reference

5-25-14-00096

EC Class

harmful

Physical and Chemical Properties

Appearance

Odorless, yellow powder.

Solubility in water

500 g/L

Melting Point

107 - 109

pKa/pKb

9.50 (pKb)

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a cool, dry place.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation.

Hazards Identification

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed.

Inhalation

May cause respiratory tract irritation.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

EC Risk Phrase

R 22 36/37/38

EC Safety Phrase

S 26 36/37/39

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Poison Class

3 (Strong toxins)

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Disposal Code

3

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents, strong acids, acid chlorides, acid anhydrides.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Transport Information

HS Code

2933 11 90