4-Aminoantipyrine
4-Aminoantipyrine Basic information
- Product Name:
- 4-Aminoantipyrine
- Synonyms:
-
- Metamizole EP Impurity B
- 4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one
- Metamizole Sodium Impurity 2（Minocycline EP Impurity B）
- 4-aminoantipirine
- 4-Amine-2,3-dimethyl-lphenyl-5-pyrazolone-[5],Ampyrone
- 4-amino-1,2-dihydro-1,5-dimethyl-2-phenyl-3h-pyrazol-3-on
- AKOS BBS-00007964
- AMINOANTIPYRINE
- CAS:
- 83-07-8
- MF:
- C11H13N3O
- MW:
- 203.24
- EINECS:
- 201-452-3
- Product Categories:
-
- PYRAMIDON
- Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
- reagent
- Heterocycles
- Intermediates & Fine Chemicals
- Metabolites & Impurities
- Pharmaceuticals
- Drug bulk
- Antibiotic Explorer
- Pyridines, Pyrimidines, Purines and Pteredines
- Mol File:
- 83-07-8.mol
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4-Aminoantipyrine Chemical Properties
- Melting point:
- 105-110 °C(lit.)
- Boiling point:
- 340 C
- Density
- 0.8
- refractive index
- 1.4930 (estimate)
- storage temp.
- Store at RT.
- solubility
- H2O: 0.1 g/mL, clear
- pka
- pK1: 4.94(+1) (25°C)
- form
- Powder or Crystals
- color
- Yellow to yellow-brown
- Odor
- Odorless
- PH
- 7.1 (100g/l, H2O, 20℃)(slurry)
- Water Solubility
- ca. 500 g/L (20 ºC)
- Merck
- 14,591
- BRN
- 181635
- Stability:
- Stable. May be light sensitive.
- CAS DataBase Reference
- 83-07-8(CAS DataBase Reference)
- NIST Chemistry Reference
- Aminoantipyrene(83-07-8)
- EPA Substance Registry System
- 4-Aminoantipyrene (83-07-8)
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Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38-20/21/22
- Safety Statements
- 26-36-36/37/39
- WGK Germany
- 3
- RTECS
- CD2480000
- F
- 8-9-23
- Hazard Note
- Harmful
- TSCA
- Yes
- HS Code
- 29331190
- Toxicity
- LD50 orally in Rabbit: 1700 mg/kg
MSDS
- Language:English Provider:Ampyrone
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
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4-Aminoantipyrine Usage And Synthesis
Chemical Properties
Amber crystalline powder
Uses
4-Aminoantipyrine is a metabolite of aminopyrine, having both analgesic and anti-inflammatory properties.
Coupling Reagent for Trinder’s reagents in colorimetric hydrogen peroxide detectionassays
Forms highly stable dyes by coupling with Trinder’s reagents in presence of Peroxidase and H2O2. Therefore suitable for use in test strip and solution diagnostics.
Uses
Indicator for trace phenol determinations in water.
Uses
A reagent for glucose determination in the presence of peroxidase and phenol
Definition
ChEBI: A pyrazolone, a member of the class of pyrazoles that is antipyrine substituted at C-4 by an amino group. It is a metabolite of aminopyrine and of metamizole.
Purification Methods
It crystallises from EtOH or EtOH/ether. [Beilstein 25 III/IV 3554.]
4-Aminoantipyrine Preparation Products And Raw materials
Preparation Products
Aminophenazone1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-3H-pyrazol-3-one AMMONIUM ALGINATEN-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)formamide
Raw materials
4-AminoantipyrineSupplier
Shanghai Aladdin Bio-Chem Technology Co.,LTD Gold
- Tel
- 021-20337333-801
- market@aladdin-e.com
Shenzhen Nexconn Pharmatechs Ltd. Gold
- Tel
- 0755-89396905-
- admin@nexconn.com;
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833- ;010-82848833-
- jkinfo@jkchemical.com;market6@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel
- 21-61259100-
- sh@meryer.com
INTATRADE GmbH
- Tel
- +49 3493/605464
- sales@intatrade.de
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4-Aminoantipyrine(83-07-8)Related Product Information
- Propyphenazone
- 4,4'-Diaminodiphenylsulfone
- N,N-Dimethylformamide
- Acetaminophen
- 4-Aminoantipyrine
- Antipyrine
- N-ACETYL-4-AMINOANTIPYRINE,Acetyl-4-aminoantipyrine,Acetylated 4-aminoantipyrine,Aminoantipyrine, N-acetyl-
- 2-CHLORO-N-(1,5-DIMETHYL-3-OXO-2-PHENYL-2,3-DIHYDRO-1H-PYRAZOL-4-YL)ACETAMIDE
- ETHYL N-(4-ANTIPYRYL)CARBAMATE
- Dimethyl sebacate
- Dimethyl sulfoxide
- 4-DiMethylaMino Antipyrine
- Cefazolin sodium salt
- Cefazolin
- Chlorodimethylphenylsilane
- Dimethyl ether
- Dimethyl fumarate
- DMC