Product Identification

Product Name

Methyl amyl ketone

Synonyms

2-Heptanone
Butylacetone
Heptan-2-one
Methyl amyl ketone

CAS

110-43-0

Formula

C7H14O

Molecular Weight

114.19

EINECS

203-767-1

RTECS

MJ5075000

RTECS Class

Primary Irritant

Merck

13,4683

Beilstein/Gmelin

1699063

Beilstein Reference

4-01-00-03318

EC Index Number

606-024-00-3

EC Class

Flammable; Harmful

Physical and Chemical Properties

Appearance

Water-white liquid with a penetrating fruity odor.

Solubility in water

0.43 g/100 mL.

Melting Point

-35

Boiling Point

150

Vapor Pressure

3

Density

0.8111 g/cm3

Partition Coefficient

1.98

Heat Of Vaporization

46.10 kJ/mol

Usage

Industrial solvent, solvent for synthetic resin finishes, fragrance ingredient in creams, lotions, perfumes, soaps & detergents, flavor ingredient in foods, inert reaction medium.

Vapor Density

3.9

Saturation Concentration

2,100 ppm at 25 C; 2,760 ppm at 25 C (calculated)

Odor threshold

About 0.020 ppm

Refractive Index

1.40935 (15 C)

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Remove contaminated clothing and shoes.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.

Handling

Wash thoroughly after handling. Use only in a well ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Hazards Identification

Inhalation

May cause respiratory tract irritation. Vapors may cause dizziness or suffocation.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Ingestion

Ingestion of large amounts may cause gastrointestinal irritation.

Hazards

Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.

EC Risk Phrase

R 10 20/22

EC Safety Phrase

S 24/25

UN (DOT)

1110

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Limited studies have generally documented little or no effect of ketones on reproduction in experimental animals. Human data is lacking. 2,5-Hexanedione has an effect on spermatogenesis in male experimental animals.

Exposure limit(s)

TLV: 50 ppm; 233 mg/m3 (ACGIH 1995-1996). OSHA PEL: TWA 100 ppm (465 mg/m3) NIOSH REL: TWA 100 ppm (465 mg/m3) NIOSH IDLH: 800 ppm

Poison Class

4

Fire Fighting Measures

Flash Point

49

Autoignition

532

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Use agent most appropriate to extinguish fire. Do NOT use straight streams of water.

Upper exp. limit

5.5

Lower exp. limit

1

Fire Potential

Moderate when exposed to heat or flame

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.

Stability and Reactivity

Disposal Code

1

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents, strong acids, bases.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Combustion Products

Irritating vapors and toxic gases, such as carbon dioxide and carbon monoxide, may be formed when involved in fire.

Transport Information

UN Number

1110

Hazard Class

3

Packing Group

III

HS Code

2914 19 90