Product Identification

Product Name

3,6-Diazaoctane-1,8-diamine

Synonyms

1,4,7,10-Tetraazadecane
3,6-Diazaoctane-1,8-diamine
N,N-bis(Aminoethyl)ethylenediamine
N,N'-Bis(2-aminoethyl)ethane-1,2-diamine
TETA
Trientine

CAS

112-24-3

Formula

C6H18N4

Molecular Weight

146.24

EINECS

203-950-6

RTECS

YE6650000

RTECS Class

Agricultural Chemical and Pesticide; Mutagen; Reproductive Effector; Primary Irritant

Merck

12,9796

Beilstein/Gmelin

605448

Beilstein Reference

4-04-00-01242

EC Index Number

612-059-00-5

EC Class

Harmful; Corrosive; Sensitising; Dangerous for the Environment

Physical and Chemical Properties

Appearance

Viscous, colorless to yellow liquid with an ammonia-like odor. Hygroscopic.

Solubility in water

Very soluble

Melting Point

12

Boiling Point

267

Vapor Pressure

0.009 (25 C)

Density

0.9817 g/cm3 (15 C)

pKa/pKb

3.93 (pKb)

Partition Coefficient

-1.88

Heat Of Vaporization

50.5 kJ/mol

Heat Of Combustion

-4541 kJ/mol

Usage

In detergents, synthesis of dyestuffs, pharmaceuticals.

Vapor Density

5.1

Saturation Concentration

<13 ppm (20 C)

Refractive Index

1.4986 (20 C)

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Treat symptomatically and supportively. Get medical aid immediately.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.

Skin

Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed.

Handling and Storage

Storage

Store in a cool, dry place. Corrosives area. Do not store in metal containers. Keep containers tightly closed.

Handling

Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Do not get in eyes, on skin, or on clothing. Do not ingest or inhale. Wash clothing before reuse. Discard contaminated shoes.

Hazards Identification

Inhalation

May cause severe irritation of the upper respiratory tract with pain, burns, and inflammation. In rare instances, exposure may cause sensitization, resulting in inflammation of the mucous membranes and in eczematous eruptions.

Skin

Harmful if absorbed through the skin. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. May cause severe irritation and possible burns.

Eyes

Causes severe eye burns. Low vapor concentrations may cause a temporary visual disturbance known as 'blue haze' or 'halo vision'.

Ingestion

May cause severe and permanent damage to the digestive tract. May cause severe gastrointestinal tract irritation with nausea, vomiting and possible burns.

Hazards

When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. May polymerize explosively when heated or involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.

EC Risk Phrase

R 21 34 43 52/53

EC Safety Phrase

S 26 36/37/39 45 61

UN (DOT)

2259

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Wear an impervious apron.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Prolonged or repeated skin contact may cause sensitization dermatitis and possible destruction and/or ulceration. Repeated exposure may cause allergic respiratory reaction (asthma).

Poison Class

3

Fire Fighting Measures

Flash Point

129

Autoignition

335

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding quantities of water until well after fire is out.

Upper exp. limit

7.2

Lower exp. limit

.7

Fire Potential

May burn but does not ignite readily.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation. Do not get water inside containers.

Stability and Reactivity

Disposal Code

5

Incompatibilities

Acids, acid chlorides, acid anhydrides, oxidizing agents, chloroformates.

Stability

Stable under normal temperatures and pressures.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2259

Hazard Class

8

Packing Group

II

HS Code

2921 29 00