Product Identification

Product Name

2-{4-[(2-Oxocyclopentyl)methyl]phenyl}propanoic acid

Synonyms

2-[4-[(2-Oxocyclopentan-1-yl)methyl]phenyl]propionic acid
2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionic acid
a-Methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic acid
Koloxo

CAS

68767-14-6

Formula

C15H18O3

Molecular Weight

246.31

Merck

12,5619

Physical and Chemical Properties

Solubility in water

0.81 g/L (25 C)

Melting Point

108.5 - 111

Boiling Point

418

Vapor Pressure

1E-7 (25 C)

Density

1.18 g/cm3 (20 C)

pKa/pKb

4.39 (pKa)

Partition Coefficient

1.87

Heat Of Vaporization

70.78 kJ/mol

Usage

Anti-inflammatory; analgesic.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Keep container tightly closed.

Hazards Identification

Inhalation

May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.

Skin

May cause skin irritation. May be harmful if absorbed through the skin.

Eyes

May cause irritation.

Ingestion

May be harmful if swallowed.

Hazards

Emits toxic fumes under fire conditions.

EC Safety Phrase

22 24/25

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.

Respirators

Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks.

Exposure Effects

Target organs or systems: G.I. System. Blood. Liver. Kidneys. Exposure can cause nausea, vomiting, diarrhea, and skin rash. Shock.

Fire Fighting Measures

Flash Point

220

Fire Fighting

Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Oxides of carbon.