Product Identification

Product Name

(2S,4R)-(-)-4-Hydroxy-2-pyrrolinecarboxylic acid

Synonyms

(-)-(2S,4R)-4-Hydroxyproline
(-)-4-Hydroxy-2-pyrrolidinecarboxylic acid
Hydroxy-L-proline
L-Hydroxyproline
L-Hypro
trans-Hydroxyproline

CAS

51-35-4

Formula

C5H9NO3

Molecular Weight

131.13

EINECS

200-091-9

RTECS

TW3586500

RTECS Class

Mutagen

Merck

13,4866

Beilstein/Gmelin

471933

Physical and Chemical Properties

Appearance

white solid. Practically odorless

Solubility in water

Very soluble

Melting Point

206

Boiling Point

296

pKa/pKb

2.14 (pKa)

Partition Coefficient

-1.39

First Aid Measures

Ingestion

Get medical aid. Wash mouth out with water.

Inhalation

Remove from exposure to fresh air immediately.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.

Handling and Storage

Storage

Store in a cool, dry place. Store in a tightly closed container.

Handling

Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.

Hazards Identification

Ingestion

The toxicological properties of this substance have not been fully investigated.

Inhalation

May cause respiratory tract irritation.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear chemical goggles. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear a chemical apron.

Respirators

A NIOSH/MSHA approved air purifying dust or mist respirator or European Standard EN 149.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide.

Transport Information

HS Code

2933 99 90