Product Identification

Product Name

2,5-Dichlorophenol

Synonyms

1-Hydroxy-2,5-dichlorobenzene

CAS

583-78-8

Formula

C6H4Cl2O

Molecular Weight

163.01

EINECS

209-520-4

RTECS

SK8600000

RTECS Class

Mutagen

Beilstein/Gmelin

1907692

Beilstein Reference

4-06-00-00942

EC Class

harmful, irritant

Physical and Chemical Properties

Appearance

Prisms (from benzene, petroleum ether) or white crystals.

Solubility in water

Slightly soluble

Melting Point

60 - 61

Boiling Point

211

Vapor Pressure

0.11 (25 C)

pKa/pKb

7.51 (pKa)

Partition Coefficient

3.06

Heat Of Vaporization

46.9 kJ/mol

Heat Of Combustion

-2748 kJ/mol

Usage

Chemical intermediate for 3,6-dichloro-o-anisic acid, the herbicide dicamba.

Vapor Density

5.6

Odor threshold

In water 30 ug/L

First Aid Measures

Ingestion

Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Do not store in metal containers.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.

Hazards Identification

Inhalation

Causes respiratory tract irritation. Can produce delayed pulmonary edema.

Skin

Causes skin irritation.

Eyes

Causes eye irritation. May cause chemical conjunctivitis.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. 1. Burning pain in mouth and throat. White necrotic lesions in mouth, esophagus and stomach. Abdominal pain, vomiting ... and bloody diarrhea. 2. Pallor, sweating, weakness, headache, dizziness, tinnitus. 3. Shock: Weak irregular pulse, hypotension, shallow respirations, cyanosis, pallor, and a profound fall in body temperature. 4. Possibly fleeting excitement and confusion, followed by unconsciousness. ... 5. Stentorous breathing, mucous rales, rhonchi, frothing at nose and mouth and other signs of pulmonary edema are sometimes seen. Characteristic odor of phenol on the breath. 6. Scanty, dark-colored ... urine ... moderately severe renal insufficiency may appear. 7. Methemoglobinemia, Heinz body hemolytic anemia and hyperbilirubinemia have been reported. ... 8. Death from respiratory, circulatory or cardiac failure. 9. If spilled on skin, pain is followed promptly by numbness.

Hazards

When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.

EC Risk Phrase

R 21/22 36/37/38

EC Safety Phrase

S 24 26 36/37/39

UN (DOT)

2020

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Effects may be delayed.

Fire Fighting Measures

Flash Point

100

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. May polymerize explosively when involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Combustible material; may burn but does not ignite readily. Extinguishing media: Use agent most appropriate to extinguish fire. Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding quantities of water until well after fire is out.

Fire Potential

This material is probably combustible.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation.

Stability and Reactivity

Disposal Code

3

Incompatibilities

Acid anhydrides, acid chlorides, strong oxidizing agents.

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Decomposition

Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2020

Hazard Class

6.1

Packing Group

III

HS Code

2908 10 00