Product Identification

Product Name

3-Aminophenol

Synonyms

3-Amino-1-hydroxybenzene
3-Hydroxyanaline
m-Aminophenol

CAS

591-27-5

Formula

C6H7NO

Molecular Weight

109.13

EINECS

209-711-2

RTECS

SJ4900000

RTECS Class

Mutagen; Reproductive Effector; Primary Irritant

Merck

13,459

Beilstein/Gmelin

636059

Beilstein Reference

4-13-00-00952

EC Index Number

612-127-00-4

EC Class

Harmful; Dangerous for the Environment

Physical and Chemical Properties

Appearance

White crystals or off-white flakes.

Solubility in water

35 g/L

Melting Point

122

Boiling Point

299

Vapor Pressure

0.0007 (25 C)

Density

1.275 g/cm3

pKa/pKb

9.70 (pKb)

Partition Coefficient

.34

Heat Of Vaporization

56.0 kJ/mol

Heat Of Combustion

-3167 kJ/mol

Usage

3-Aminophenol has been used as a stabilizer of chlorine-containing thermoplastics, although its principal use is as an intermediate in the production of 4-amino-2-hydroxybenzoic acid this isomer is also employed as a hair colorant and as a coupler molecule in hair dyes.

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Skin

Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a cool, dry place. Keep container closed when not in use.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.

Skin

Causes skin irritation.

Eyes

Causes eye irritation.

Ingestion

May cause irritation of the digestive tract. Causes gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.

Hazards

Containers may explode when heated.

EC Risk Phrase

R 20/22 51/53

EC Safety Phrase

S 28 61

UN (DOT)

2512

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

May cause reproductive and fetal effects.

Exposure limit(s)

OEL-RUSSIA:STEL 1 mg/m3

Poison Class

4

Fire Fighting Measures

Flash Point

92

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Fire Potential

This material is probably combustible.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal.

Stability and Reactivity

Disposal Code

3

Incompatibilities

Acids, acid chlorides, acid anhydrides, chloroformates, strong oxidizing agents.

Stability

Stable under normal temperatures and pressures.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2512

Hazard Class

6.1

Packing Group

III

HS Code

2922 29 00