Product Identification

Product Name

O-6-Amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1-2-3)-o-beta-D-talopyranosyl-(1-5)-2-deoxy-N3-methyl-D-streptamine

Synonyms

5-O-(2,3-O-(6-Amino-6-desoxyheptapyranosyliden)-beta-D-talopyranosyl)-desoxy-N'-methyl-D-streptamin
Antihelmycin
Hydromycin B
Hygromix 2.4
Hygromix 8
Hygrovetine

CAS

31282-04-9

Formula

C20H37N3O13

Molecular Weight

527.53

EINECS

250-545-5

RTECS

WK2130000

RTECS Class

Drug; Mutagen; Natural Product

Merck

12,4901

Beilstein/Gmelin

6755837

Physical and Chemical Properties

Melting Point

160

pKa/pKb

4.50 (pKb)

Usage

Antibiotic that kills bacteria, fungi and higher eukaryotic cells by inhibiting protein synthesis.

First Aid Measures

Ingestion

If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. MMEDIATELY transport the victim to a hospital.

Inhalation

IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.

Skin

IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.

Eyes

First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Handling and Storage

Storage

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation

May be irritating to mucous membranes and upper respiratory tract. May be fatal if inhaled. May cause allergic reactions.

Skin

Causes irritation. May be fatal if absorbed through the skin. May cause allergic skin reaction.

Eyes

Causes severe irritation.

Ingestion

May be fatel if swallowed.

EC Risk Phrase

26/27/28 41 42/43

EC Safety Phrase

22 26 28 36/37/39 45

UN (DOT)

3462

Exposure Controls/Personal Protection

Personal Protection

If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.

Respirators

Wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). Splash proof safety goggles should be worn while handling this chemical. Alternatively, a full face respirator, equipped as above, may be used to provide simultaneous eye and respiratory protection.

Exposure Effects

Targets ears. Signs and symptoms of exposure include dermatitis, conjunctivitis, burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea and vomiting. Repeated exposure can cause hearing loss.

Fire Fighting Measures

Fire Fighting

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.

Accidental Release Measures

Small spills/leaks

If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Oxides of carbon and nitrogen.

Transport Information

UN Number

3462

Hazard Class

6.1

Packing Group

I