Product Identification

Product Name

Pyridine sulfur trioxide

Synonyms

Pyridine, compound with sulfur trioxide (1:1)

CAS

26412-87-3

Formula

C5H5NO3S

Molecular Weight

159.16

EINECS

247-683-3

Beilstein/Gmelin

3704116

Beilstein Reference

5-20-05-00184

EC Class

harmful, irritant

Physical and Chemical Properties

Appearance

White to beige powder.

Solubility in water

Decomposition

Melting Point

155 - 165

Usage

Used as an activating electrophile in a swern like oxidation.

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from water.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Hazards Identification

Ingestion

May be harmful if swallowed. Causes digestive tract irritation.

Inhalation

Causes respiratory tract irritation. Causes irritation of mucous membrane.

Skin

Causes mild skin irritation.

Eyes

Causes severe eye irritation.

EC Risk Phrase

R 22 34

EC Safety Phrase

S 26 36/37/39 45

UN (DOT)

3261

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Fire Fighting Measures

Autoignition

> 350

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water spray, dry chemical, carbon dioxide, or alcohol-resistant foam.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal.

Stability and Reactivity

Disposal Code

12

Incompatibilities

Metals, strong oxidizing agents, moisture, diphenylmercury.

Stability

Stable under normal temperatures and pressures.

Decomposition

Nitrogen oxides, carbon monoxide, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Transport Information

UN Number

3261

HS Code

2942 00 00