Product Identification

Product Name

Ethyl 2-isopropylacetoacetate

Synonyms

2-Acetyl-3-methylbutyric acid ethyl ester
2-Isopropyl-3-oxobutanoic acid ethyl ester
Acetoacetic acid, 2-isopropyl-, ethyl ester
Butanoic acid, 2-acetyl-3-methyl-, ethyl ester
Ethyl 2-isopropylacetoacetate
Ethyl a-isopropylacetoacetate

CAS

1522-46-9

Formula

C9H16O3

Molecular Weight

172.22

EINECS

216-192-6

Beilstein/Gmelin

636360

Physical and Chemical Properties

Appearance

Clear, colorless liquid.

Solubility in water

3.9 g/L (25 C)

Melting Point

-20

Boiling Point

201

Vapor Pressure

0.03 (25 C)

Density

0.962 g/cm3 (20 C)

pKa/pKb

12.28 (pKa)

Partition Coefficient

1.94

Heat Of Vaporization

44.34 kJ/mol

Refractive Index

1.425 (20 C)

Hazards Identification

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Hazards

Emits toxic fumes under fire conditions.

EC Safety Phrase

23 24/25

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.

Fire Fighting Measures

Flash Point

76

Fire Fighting

For small (incipient) fires, use media such as 'alcohol' foam, dry chemical, or carbon dioxide. For large fires, apply water from as far as possible. Use very large quantities (flooding) of water applied as a mist or spray; solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Ventilate area and wash spill site after material pickup is complete. Absorb on sand or vermiculite and place in closed containers for disposal. Wash spill site with soap solution. Flush spill area with copious amounts of water.