Product Identification

Product Name

C.I. 45380

Synonyms

2',4',5',7'-Tetrabromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H), 9'-[9H]xanthan]-3-one disodium salt
2',4',5',7'-Tetrabromofluorescein
Acid red 87
Bromofluorescein
Disodium 2-(2,4,5,7-tetrabromo-3-oxido-6-oxoxanthen-9-yl)benzoate

CAS

17372-87-1

Formula

C20H6Br4Na2O5

Molecular Weight

691.86

EINECS

241-409-6

RTECS

LM5850000

RTECS Class

Tumorigen; Mutagen

Merck

13,3634

Beilstein/Gmelin

3586809

EC Class

irritant

Physical and Chemical Properties

Appearance

Red crystals

Solubility in water

Soluble

Melting Point

295 - 296

pKa/pKb

2.9, 4.5(at 25℃) (pKa)

Partition Coefficient

6.92

Usage

Red dye used in cosmetics, pharmaceuticals, textiles, etc., And as tissue stain, vital stain, and counterstain with hematoxylin. It is also used in special culture media.

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a cool, dry place. Keep container closed when not in use.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Avoid ingestion and inhalation.

Hazards Identification

Ingestion

May cause irritation of the digestive tract.

Inhalation

May cause respiratory tract irritation.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

EC Risk Phrase

R 36

EC Safety Phrase

S 22 24/25

UN (DOT)

1987

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Poison Class

4

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizers.

Decomposition

Carbon monoxide, carbon dioxide, hydrogen bromide, sodium oxide, bromine fumes.

Transport Information

UN Number

1987

HS Code

3204 12 00